公开(公告)号：US07708991B2

公开(公告)日：2010-05-04

申请号：US11058542

申请日：2005-02-15

Applicant: Laurence A Cole

Inventor： Laurence A Cole

IPC: A61K39/395

CPC classification number: C07K16/26 ,  A61K2039/505 ,  C07K2317/73 ,  C07K2317/76

Abstract: The present invention relates to compositions and methods for treating cancer, especially epithelial and eutopic cancers using inhibitors of H-HCG or β-H-HCG, as well as vaccines for use in oncostasis or reducing the likelihood of recurrence of cancer after remission. In addition, the present invention provides a method for reducing the likelihood that a woman will become pregnant or that an unwanted pregnancy may be terminated.

Abstract translation: 本发明涉及使用H-HCG或HGF-HCG抑制剂治疗癌症，特别是上皮和非特异性癌症的组合物和方法，以及用于止血或降低缓解后癌症复发可能性的疫苗。 此外，本发明提供了一种降低女性怀孕或可能终止意外怀孕的可能性的方法。

公开(公告)号：US07314760B2

公开(公告)日：2008-01-01

申请号：US10862791

申请日：2004-06-07

Applicant: Laurence A Cole ,  Jaime M Riley

Inventor： Laurence A Cole ,  Jaime M Riley

IPC: G01N33/48 ,  G01N33/50 ,  A61K38/24

CPC classification number: G01N33/76 ,  G01N2333/59

Abstract: The invention provides prenatal screening methods for Down's syndrome. Specifically, the methods of the invention comprise determining the amount of hyperglycosylated human chorionic gonadotropin (hCG) charge isoforms in a biological sample from a pregnant woman and comparing the amount of highly acidic and less acidic isoforms with those found in a sample taken from a pregnant woman carrying a normal fetus. The methods of the invention can be employed during any stage of pregnancy.

Abstract translation: 本发明提供唐氏综合征的产前筛查方法。 具体地说，本发明的方法包括确定来自孕妇的生物样品中高糖基化的人绒毛膜促性腺激素（hCG）电荷同种型的量，并将高度酸性和酸性较弱的同种型的量与从怀孕 携带正常胎儿的女人 本发明的方法可以在怀孕的任何阶段中使用。