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    ADJUVANT FOR THE PREPARATION OF VACCINE COMPOSITIONS INTENDED FOR THE PREVENTION OF COCCIDIOSIS
    2.
    发明申请
    ADJUVANT FOR THE PREPARATION OF VACCINE COMPOSITIONS INTENDED FOR THE PREVENTION OF COCCIDIOSIS 有权
    适用于预防预防结核病的疫苗组合物的准备

    公开(公告)号：US20120308604A1

    公开(公告)日：2012-12-06

    申请号：US13575971

    申请日：2011-01-14

    申请人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    发明人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    IPC分类号： A61K47/06 ,  A61P33/02 ,  A61K39/012

    CPC分类号： A61K39/39 ,  A61K39/012 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/57

    摘要： A vaccine adjuvant which, based on the 100% mass thereof, includes between 10% and 95% of a mineral oil containing: between 0.05 mass-% and 10 mass-% hydrocarbon chains having less than 16 carbon atoms, and between 0.05 mass-% and 5 mass-% hydrocarbon chains having more than 28 carbon atoms. In addition, the adjuvant has a P/N ratio, corresponding to the ratio of the mass quantity of the paraffinic hydrocarbon chains to the mass quantity of the naphthenic hydrocarbon chains, of between 2.5 and 3, the adjuvant being intended for the production of a vaccine composition to prevent coccidiosis.

    摘要翻译： 基于其100％质量的疫苗佐剂包含10％至95％的矿物油，其含有0.05质量％至10质量％的碳原子数小于16的烃链和0.05质量％ 具有大于28个碳原子的％和5质量％烃链。 此外，佐剂对应于石蜡烃链的质量与环烷烃链的质量之比的P / N比在2.5和3之间，所述佐剂用于生产 疫苗组合物以预防球虫病。

    Adjuvant for the preparation of vaccine compositions intended for the prevention of coccidiosis
    3.
    发明授权
    Adjuvant for the preparation of vaccine compositions intended for the prevention of coccidiosis 有权
    用于制备旨在预防球虫病的疫苗组合物的佐剂

    公开(公告)号：US08703154B2

    公开(公告)日：2014-04-22

    申请号：US13575971

    申请日：2011-01-14

    申请人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    发明人： Laurent Dupuis ,  Francois Bertrand ,  Sebastien Deville

    IPC分类号： A61K39/39 ,  A61K39/012

    CPC分类号： A61K39/39 ,  A61K39/012 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/57

    摘要： A vaccine adjuvant which, based on the 100% mass thereof, includes between 10% and 95% of a mineral oil containing: between 0.05 mass-% and 10 mass-% hydrocarbon chains having less than 16 carbon atoms, and between 0.05 mass-% and 5 mass-% hydrocarbon chains having more than 28 carbon atoms. In addition, the adjuvant has a P/N ratio, corresponding to the ratio of the mass quantity of the paraffinic hydrocarbon chains to the mass quantity of the naphthenic hydrocarbon chains, of between 2.5 and 3, the adjuvant being intended for the production of a vaccine composition to prevent coccidiosis.

    摘要翻译： 基于其100％质量的疫苗佐剂包含10％至95％的矿物油，其含有0.05质量％至10质量％的碳原子数小于16的烃链和0.05质量％ 具有大于28个碳原子的％和5质量％烃链。 此外，佐剂对应于石蜡烃链的质量与环烷烃链的质量之比的P / N比在2.5和3之间，所述佐剂用于生产 疫苗组合物以预防球虫病。

    ADJUVANT DILUENTS FOR LIVE VACCINES FOR PIG DISEASES
    4.
    发明申请
    ADJUVANT DILUENTS FOR LIVE VACCINES FOR PIG DISEASES 审中-公开
    用于皮肤疾病的活疫苗的补充剂

    公开(公告)号：US20130011434A1

    公开(公告)日：2013-01-10

    申请号：US13636741

    申请日：2011-03-15

    申请人： Francois Bertrand ,  Sebastien Deville ,  Laurent Dupuis

    发明人： Francois Bertrand ,  Sebastien Deville ,  Laurent Dupuis

    IPC分类号： A61K39/12 ,  A61P31/14 ,  A61P37/04

    CPC分类号： A61K39/12 ,  A61K2039/5254 ,  A61K2039/552 ,  A61K2039/55555 ,  A61K2039/55566 ,  C12N2770/10034 ,  C12N2770/10051

    摘要： A method for preparing an injectable vaccine composition intended to combat porcine reproductive and respiratory syndrome (PRRS), includes at least the step in which: a) a live vaccine is mixed extemporaneously with an adjuvant diluent (AD). The adjuvant diluent is an oil-in-water-type emulsion or an oil-in-water-type microemulsion, or an aqueous solution including water and at least one inorganic salt selected from aluminum hydroxide, cerium nitrate, zinc sulfate, colloidal iron hydroxide or calcium chloride, salts of divalent or trivalent metals or sympathomimetic compounds.

    摘要翻译： 制备旨在对抗猪繁殖与呼吸综合征（PRRS）的可注射疫苗组合物的方法至少包括以下步骤：a）活疫苗与佐剂稀释剂（AD）同时混合。 助剂稀释剂是水包油型乳剂或水包油型微乳液，或水包括水和至少一种选自氢氧化铝，硝酸铈，硫酸锌，胶态氢氧化铁的无机盐的水溶液 或氯化钙，二价或三价金属或拟交替物质的盐。