公开(公告)号：US20180353611A1

公开(公告)日：2018-12-13

申请号：US16005245

申请日：2018-06-11

Applicant: LegoChem Biosciences, Inc.

Inventor： Yong Zu Kim ,  Tae Kyo Park ,  Sung Ho Woo ,  Sun Young Kim ,  Jung Un Cho ,  Doo Hwan Jung ,  Ji Young Min ,  Hyang Sook Lee ,  Yun Hee Park ,  Jeong Hee Ryu ,  Kyu Man Oh ,  Yeong Soo Oh ,  Jeiwook Chae ,  Ho Young Song ,  Chul-Woong Chung ,  Jeon Yang

IPC: A61K47/68 ,  C07K19/00 ,  C07K16/32 ,  C07D519/00 ,  C07D487/04 ,  C07D249/04 ,  A61K47/54 ,  A61K47/69 ,  A61K39/00

CPC classification number: A61K47/6871 ,  A61K47/50 ,  A61K47/549 ,  A61K47/6801 ,  A61K47/6803 ,  A61K47/6811 ,  A61K47/6813 ,  A61K47/6855 ,  A61K47/6889 ,  A61K47/69 ,  A61K2039/505 ,  C07D249/04 ,  C07D487/04 ,  C07D519/00 ,  C07K16/32 ,  C07K19/00 ,  C07K2317/24 ,  C07K2317/94

Abstract: Provided are compounds comprising a self-immolative group, and the compounds comprising a self-immolative group according to the present invention may include a protein (for example, an oligopeptide, a polypeptide, an antibody, or the like) having substrate-specificity for a target and an active agent (for example, a drug, a toxin, a ligand, a detection probe, or the like) having a specific function or activity.