公开(公告)号：US4059405A

公开(公告)日：1977-11-22

申请号：US715855

申请日：1976-08-19

申请人： Lester A. Sodickson ,  Franklin Lim

发明人： Lester A. Sodickson ,  Franklin Lim

IPC分类号： C12Q1/00 ,  G01N33/52 ,  G01N21/24 ,  G01N33/16

CPC分类号： G01N33/52 ,  C12Q1/00 ,  Y10T436/110833 ,  Y10T436/144444

摘要： An optically-thin preparation of a sample solution and chemical reagents produces a constituent-manifesting reaction product that can be measured in linear relation to the concentration of the constituent of interest. A fibrous sheet contains the sample and the reagents for both the reaction and the measurement. The same site on the fibrous sheet which bears the reacting materials serves as a blank to produce a reference signal for the measurement.

摘要翻译： 样品溶液和化学试剂的光学薄的制备产生可以与感兴趣成分的浓度成线性关系测量的成分表现的反应产物。 纤维片含有样品和用于反应和测量的试剂。 带有反应材料的纤维片上的相同部位用作空白，以产生用于测量的参考信号。

公开(公告)号：US3937614A

公开(公告)日：1976-02-10

申请号：US501133

申请日：1974-08-28

申请人： Lester A. Sodickson ,  Franklin Lim

发明人： Lester A. Sodickson ,  Franklin Lim

IPC分类号： G01N33/483 ,  G01N21/38 ,  G01N21/48

CPC分类号： G01N33/487

摘要： A press for compressing a liquid-bearing absorbent article to transfer a portion of the liquid materials to a contiguous article has two concentric pressure feet. One is an outer foot member that bears against the liquid-bearing article along the periphery of the pressure area, and the other is an inner, deformable and contoured foot member that applies pressure to the liquid-bearing article progressively along the pressure area. A photometer can be combined with the press to measure constituents or other properties of the liquid materials being transferred.

公开(公告)号：US4298345A

公开(公告)日：1981-11-03

申请号：US25497

申请日：1979-03-30

申请人： Lester A. Sodickson ,  Franklin Lim

发明人： Lester A. Sodickson ,  Franklin Lim

IPC分类号： G01N21/86 ,  G01N33/52 ,  G01N1/14 ,  G01N21/27

CPC分类号： G01N21/8483 ,  G01N33/528

摘要： Chemical analysis of a sample with reagents spotted on a fibrous or porous medium employs a medium pretreated both with reagents and with conditioning agent. The conditioning agent increases the degree to which the liquid reactants wet the medium. One form of pretreated medium has different reagents located predominantly within different selected zones.Liquid is applied to the medium, typically as diluted sample, at a rate selected to enhance formation of repeatable spots. In one embodiment the liquid is applied by flowing it onto a wick element seated on the medium. The wick is disc-like and small relative to the spot which the reactants form on the medium. The disc can be pretreated to carry reagent, which the liquid transfers to the medium.The analysis instrument receives a reaction medium between selectively recessed upper and lower surfaces aligned in opposition at the reaction spot being analyzed.The analysis can, depending on the analytical reaction, the medium and the precision required, proceed while the reactants are wet or can measure a reaction product after the reactants are dry. A single point analysis can also be made.

摘要翻译： 使用在纤维或多孔介质上点样的试剂的样品的化学分析采用预处理试剂和调理剂的培养基。 调理剂增加液体反应物湿润介质的程度。 一种形式的预处理介质具有主要位于不同选择区域内的不同试剂。 将液体通常以稀释的样品施加到介质上，速率被选择以增强可重复斑点的形成。 在一个实施例中，通过将液体流动到坐在介质上的芯片元件上来施加液体。 相对于反应物在介质上形成的点，芯是盘状的和小的。 该盘可以预处理以携带试剂，液体转移到介质中。

公开(公告)号：US4386895A

公开(公告)日：1983-06-07

申请号：US320881

申请日：1981-11-13

申请人： Lester A. Sodickson

发明人： Lester A. Sodickson

IPC分类号： B01J13/04 ,  B28B1/54

CPC分类号： B01J13/046

摘要： Disclosed is an apparatus for producing capsules of the type which are formed by immersing liquid droplets in a gelling agent. The apparatus comprises a rotor disposed about a central axis of rotation which houses a reservoir for holding the liquid to be formed into capsules, and conduits which lead to ports spaced uniformly on the circumference of a circle. When the rotor is actuated, spheroidal droplets of the capsule-forming material take shape at the ports and are propelled radially outwardly into a gelling agent contained in a reservoir which comprises an annular surface spaced radially apart from the ports.

摘要翻译： 公开了一种用于生产通过将液滴浸入胶凝剂中形成的胶囊的装置。 该装置包括围绕中心旋转轴线设置的转子，其容纳用于保持要形成为胶囊的液体的储存器，以及导向在圆周上均匀间隔开的端口的导管。 当转子被致动时，胶囊形成材料的球形液滴在端口处形成并被径向向外推进到包含在储存器中的胶凝剂中，该储存器包括与端口径向分开的环形表面。

公开(公告)号：US4178153A

公开(公告)日：1979-12-11

申请号：US853435

申请日：1977-11-21

申请人： Lester A. Sodickson

发明人： Lester A. Sodickson

IPC分类号： G01N21/78 ,  G01N21/86 ,  G01N33/52 ,  G01N33/16 ,  G01N21/24

CPC分类号： G01N21/8483 ,  G01N33/525 ,  Y10T436/144444

摘要： Chemical analysis of a sample with reagents spotted on a fibrous or porous medium employs a medium pretreated both with reagents and with conditioning agent. The conditioning agent increases the degree to which the liquid reactants wet the medium. One form of pretreated medium has different reagents located predominantly within different selected zones.Liquid is applied to the medium, typically as diluted sample, at a rate selected to enhance formation of repeatable spots. In one embodiment the liquid is applied by flowing it onto a wick element seated on the medium. The wick is disc-like and small relative to the spot which the reactants form on the medium. The disc can be pretreated to carry reagent, which the liquid transfers to the medium.The analysis instrument receives a reaction medium between selectively recessed upper and lower surfaces aligned in opposition at the reaction spot being analyzed.The analysis can, depending on the analytical reaction, the medium and the precision required, proceed while the reactants are wet or can measure a reaction product after the reactants are dry. A single point analysis can also be made.

摘要翻译： 使用在纤维或多孔介质上点样的试剂的样品的化学分析采用预处理试剂和调理剂的培养基。 调理剂增加液体反应物湿润介质的程度。 一种形式的预处理介质具有主要位于不同选择区域内的不同试剂。 将液体通常以稀释的样品施加到介质上，速率被选择以增强可重复斑点的形成。 在一个实施例中，通过将液体流动到坐在介质上的芯片元件上来施加液体。 相对于反应物在介质上形成的点，芯是盘状的和小的。 该盘可以预处理以携带试剂，液体转移到介质中。 分析仪器在被分析的反应点处相对地对准地选择性地凹入的上表面和下表面之间接收反应介质。 分析可以根据分析反应，所需的介质和精度，当反应物湿润或在反应物干燥后可以测量反应产物时进行。 也可以进行单点分析。