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公开(公告)号:US20130004517A1
公开(公告)日:2013-01-03
申请号:US13608166
申请日:2012-09-10
申请人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen Haggarty
发明人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen Haggarty
IPC分类号: A61K39/395 , A61K31/40 , A61K31/445 , A61K31/496 , A61K31/7056 , C12N5/079 , A61P25/28 , A61P25/18 , A61P25/24 , A61P25/30 , A61P25/16 , A61K31/5383 , A61P25/00
CPC分类号: A61K38/1709 , A61K31/00 , A61K31/351 , A61K31/40
摘要: The invention relates to methods of treating neurological disorders in a subject, by activating a DISC1 pathway. Methods of promoting neurogenesis in adult neural progenitor cells, enhancing nerve generation and treating GSK3 disorders as well as related compositions are also provided.
摘要翻译: 本发明涉及通过激活DISC1途径治疗受试者神经障碍的方法。 还提供了促进成年神经祖细胞神经发生,增强神经产生和治疗GSK3疾病以及相关组合物的方法。
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公开(公告)号:US20100015130A1
公开(公告)日:2010-01-21
申请号:US12474229
申请日:2009-05-28
申请人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen Haggarty
发明人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen Haggarty
IPC分类号: A61K39/395 , A61K38/00 , A61K31/496 , A61K31/445 , C07D409/14 , C07D211/08 , C07D207/14 , C07D405/14 , A61P29/00 , A61P37/00 , A61P25/00
CPC分类号: A61K38/1709 , A61K31/00 , A61K31/351 , A61K31/40
摘要: The invention relates to methods of treating neurological disorders in a subject, by activating a DISC1 pathway. Methods of promoting neurogenesis in adult neural progenitor cells, enhancing nerve generation and treating GSK3 disorders as well as related compositions are also provided.
摘要翻译: 本发明涉及通过激活DISC1途径治疗受试者神经障碍的方法。 还提供了促进成年神经祖细胞神经发生,增强神经产生和治疗GSK3疾病以及相关组合物的方法。
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公开(公告)号:US10124035B2
公开(公告)日:2018-11-13
申请号:US13608166
申请日:2012-09-10
申请人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen J. Haggarty
发明人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen J. Haggarty
摘要: The invention relates to methods of treating neurological disorders in a subject, by activating a DISC1 pathway. Methods of promoting neurogenesis in adult neural progenitor cells, enhancing nerve generation and treating GSK3 disorders as well as related compositions are also provided.
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公开(公告)号:US08263547B2
公开(公告)日:2012-09-11
申请号:US12474229
申请日:2009-05-28
申请人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen J. Haggarty
发明人: Li-Huei Tsai , Yingwei Mao , Jon Madison , Stephen J. Haggarty
CPC分类号: A61K38/1709 , A61K31/00 , A61K31/351 , A61K31/40
摘要: The invention relates to methods of treating neurological disorders in a subject, by activating a DISC1 pathway. Methods of promoting neurogenesis in adult neural progenitor cells, enhancing nerve generation and treating GSK3 disorders as well as related compositions are also provided.
摘要翻译: 本发明涉及通过激活DISC1途径治疗受试者神经障碍的方法。 还提供了促进成年神经祖细胞神经发生,增强神经产生和治疗GSK3疾病以及相关组合物的方法。
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