公开(公告)号：US20210108253A1

公开(公告)日：2021-04-15

申请号：US16497615

申请日：2018-03-29

Applicant: Life Technologies Corporation

Inventor： Andrew DIX ,  Jeffrey Monette

IPC: C12Q1/6818 ,  C12Q1/6876

Abstract: The present disclosure is directed to methods and kits for detection and/or quantification of nucleic acids, such as double stranded DNA that is used in next-generation sequencing (NGS) applications. Nucleic acid-based probes, such as peptide nucleic acid (PNA) oligomers, molecular beacons, DNA flares and locked nucleic acid (LNA) oligomers, are also provided for use in the methods and kits of the present disclosure.

公开(公告)号：US20220195499A1

公开(公告)日：2022-06-23

申请号：US17569245

申请日：2022-01-05

Applicant: Life Technologies Corporation

Inventor： Andrew DIX ,  Jeffrey Monette

IPC: C12Q1/6818 ,  C12Q1/6876

Abstract: The present disclosure is directed to methods and kits for detection and/or quantification of nucleic acids, such as double stranded DNA that is used in next-generation sequencing (NGS) applications. Nucleic acid-based probes, such as peptide nucleic acid (PNA) oligomers, molecular beacons, DNA flares and locked nucleic acid (LNA) oligomers, are also provided for use in the methods and kits of the present disclosure.