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公开(公告)号:US06242419B1
公开(公告)日:2001-06-05
申请号:US09383586
申请日:1999-08-26
申请人: Lorna Strachan , Matthew Sleeman , Nevin Abernethy , Rene Onrust , Anand Kumble , Greg Murison
发明人: Lorna Strachan , Matthew Sleeman , Nevin Abernethy , Rene Onrust , Anand Kumble , Greg Murison
IPC分类号: A01N3718
摘要: Isolated polynucleotides encoding polypeptides expressed in mammalian fsn -/- lymph node stromal cells are provided, together with expression vectors and host cells comprising such isolated polynucleotides. In certain embodiments such polynucleotides encode members of the fibroblast growth factor receptor family. Methods for the use of such polynucleotides and polypeptides are also provided.
摘要翻译: 提供编码在哺乳动物fsn - / - 淋巴结基质细胞中表达的多肽的分离的多核苷酸以及包含这种分离的多核苷酸的表达载体和宿主细胞。 在某些实施方案中,所述多核苷酸编码成纤维细胞生长因子受体家族的成员。 还提供了使用这种多核苷酸和多肽的方法。