公开(公告)号：US5252191A

公开(公告)日：1993-10-12

申请号：US690684

申请日：1991-04-24

申请人： Louis F. Pauli ,  Alphons Dufourny ,  Robert B. Koolstra ,  Hans Wynberg ,  Wolter Ten Hoeve

发明人： Louis F. Pauli ,  Alphons Dufourny ,  Robert B. Koolstra ,  Hans Wynberg ,  Wolter Ten Hoeve

IPC分类号： C07B37/08 ,  C07C401/00 ,  C07D333/18 ,  C07D333/20 ,  C07D333/36 ,  C07D409/04 ,  C07D409/06 ,  C07D409/14 ,  C07J7/00 ,  C07G13/00

CPC分类号： C07D409/04 ,  C07C401/00 ,  C07D333/20 ,  C07D333/36 ,  C07D409/14

摘要： The invention relates to a method for the photochemical isomerization of organic compounds, in particular for the photochemical conversion of tachysterol compounds into previtamin D compounds and of trans-vitamin D compounds into cis-vitamin D compounds, under the influence of radiation, by exposing a solution of the organic compound to be converted in the presence of a non-polymeric photosensitizer to light with approx. 300-1,000 nm wavelength, and by then isolating the resulting product, wherein a substituted thiophene derivative having a substantial absorption in said wavelength region is used as the photosensitizer. The invention also relates to a new photosensitizer to be used for said isomerization reaction.