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公开(公告)号：US20220213543A1
公开(公告)日：2022-07-07
申请号：US17688424
申请日：2022-03-07
发明人： Chunxiao Song , Yibin Liu
IPC分类号： C12Q1/6869 , C12P17/16 , C12Q1/6844 , C12Q1/6874 , C12Q1/6876
摘要： This disclosure provides methods for bisulfite-free identification in a nucleic acid sequence of the locations of 5-methylcytosine, 5-hydroxymethylcytosine, 5-carboxylcytosine and 5-formylcytosine.
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公开(公告)号：US20200370114A1
公开(公告)日：2020-11-26
申请号：US16960510
申请日：2019-01-08
发明人： Chunxiao Song , Yibin Liu
IPC分类号： C12Q1/6869 , C12P17/16
摘要： This disclosure provides methods for bisulfite-free identification in a nucleic acid sequence of the locations of 5-methyl-cytosine, 5-hydroxymethylcytosine, 5-carboxylcytosine and 5-formylcytosine.
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公开(公告)号：US11306355B2
公开(公告)日：2022-04-19
申请号：US17201825
申请日：2021-03-15
发明人： Chunxiao Song , Yibin Liu
IPC分类号： C12Q1/6869 , C12P17/16 , C12Q1/6844 , C12Q1/6874 , C12Q1/6876
摘要： This disclosure provides methods for bisulfite-free identification in a nucleic acid sequence of the locations of 5-methylcytosine, 5-hydroxymethylcytosine, 5-carboxylcytosine and 5-formylcytosine.
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公开(公告)号：US20200224190A1
公开(公告)日：2020-07-16
申请号：US16645739
申请日：2018-09-11
发明人： Chunxiao Song , Paulina Siejka
IPC分类号： C12N15/10 , C12Q1/6874
摘要： The present disclosure provides methods for selectively tagging 5-methylcytosine in a DNA sample and using this approach for genome-wide profiling of 5-methylcytosine in a low input DNA sample such as circulating cell-free DNA.
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公开(公告)号：US20220282323A1
公开(公告)日：2022-09-08
申请号：US17688427
申请日：2022-03-07
发明人： Chunxiao Song , Yibin Liu
IPC分类号： C12Q1/6869 , C12P17/16 , C12Q1/6844 , C12Q1/6874 , C12Q1/6876
摘要： This disclosure provides methods for bisulfite-free identification in a nucleic acid sequence of the locations of 5-methylcytosine, 5-hydroxymethylcytosine, 5-carboxylcytosine and 5-formylcytosine.
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公开(公告)号：US20210317519A1
公开(公告)日：2021-10-14
申请号：US17201825
申请日：2021-03-15
发明人： Chunxiao Song , Yibin Liu
IPC分类号： C12Q1/6869 , C12P17/16
摘要： This disclosure provides methods for bisulfite-free identification in a nucleic acid sequence of the locations of 5-methylcytosine, 5-hydroxymethylcytosine, 5-carboxylcytosine and 5-formylcytosine.
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