公开(公告)号：US20240201207A1

公开(公告)日：2024-06-20

申请号：US18287532

申请日：2022-04-19

申请人： MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT

发明人： Florian Herse ,  Louise Bjorkholt Andersen ,  Andreas Busjahn ,  Ralf Dechend

IPC分类号： G01N33/92

CPC分类号： G01N33/92 ,  G01N2333/475 ,  G01N2333/912 ,  G01N2800/368 ,  G01N2800/50

摘要： The invention pertains to a method for the prediction of preeclampsia in a pregnant female human subject until the end of gestational week 16 of pregnancy based on metabolites from a blood sample obtained from said subject. According to the invention, the method comprises the following steps:



measuring the level of the following metabolites in the sample: 14,15-DHET, 13-HODE, 10,11-EDP, 21-HDHA, and 11,12-DHET, and
concluding based on the measured level whether the subject is likely to develop preeclampsia.