公开(公告)号：US10675244B2

公开(公告)日：2020-06-09

申请号：US15959521

申请日：2018-04-23

申请人： MDIMUNE INC.

发明人： Yong Song Gho ,  Yoon Keun Kim ,  Su Chul Jang ,  Oh Youn Kim ,  Dong-Sic Choi ,  Yae Jin Yoon

IPC分类号： A61K9/127 ,  A61K9/50 ,  A61K45/06 ,  A61K35/15 ,  A61K35/545

摘要： The present invention relates to a microvesicle that is derived from nucleated mammalian cells, which are smaller than the nucleated cells. The microvesicles of the present invention can be used in the delivery of a therapeutic or diagnostic substance to specific tissues or cells, and more particularly, relates to microvesicles derived from monocytes, macrophages, dendritic cells, stem cells or the like, which can be used to deliver specific therapeutic or diagnostic substances for treating and/or diagnosing tissue associated with cancer, diseased blood vessels, inflammation, or the like.

公开(公告)号：US20180296483A1

公开(公告)日：2018-10-18

申请号：US15959521

申请日：2018-04-23

申请人： MDIMUNE INC.

发明人： Yong Song Gho ,  Yoon Keun Kim ,  Su Chul Jang ,  Oh Youn KIM ,  Dong-Sic CHOI ,  Yae Jin YOON

IPC分类号： A61K9/127 ,  A61K35/545 ,  A61K45/06 ,  A61K35/15 ,  A61K9/50

CPC分类号： A61K9/127 ,  A61K9/1278 ,  A61K9/5068 ,  A61K35/15 ,  A61K35/545 ,  A61K45/06 ,  A61K2300/00

摘要： The present invention relates to a microvesicle that is derived from nucleated mammalian cells, which are smaller than the nucleated cells. The microvesicles of the present invention can be used in the delivery of a therapeutic or diagnostic substance to specific tissues or cells, and more particularly, relates to microvesicles derived from monocytes, macrophages, dendritic cells, stem cells or the like, which can be used to deliver specific therapeutic or diagnostic substances for treating and/or diagnosing tissue associated with cancer, diseased blood vessels, inflammation, or the like.