公开(公告)号：US20180155339A1

公开(公告)日：2018-06-07

申请号：US15528282

申请日：2015-11-17

Applicant: MERCK PATENT GMBH

Inventor： Andreas WAECHTLER ,  Hadia SALEH-KASSIM ,  Christian JASPER ,  Joern KOLB ,  David MAILLARD

IPC: C07D471/04 ,  C07B55/00 ,  C07B57/00 ,  C07C31/30

CPC classification number: C07D471/04 ,  C07B55/00 ,  C07B57/00 ,  C07B2200/07 ,  C07C31/30

Abstract: The present invention relates to a method for the racemization of enantiomerically pure or enantiomerically enriched Praziquantel under basic conditions and a method for the production of (R)-Praziquantel in enantiopure or enantiomerically enriched form, which comprises the racemization method.