公开(公告)号：US20160178620A1

公开(公告)日：2016-06-23

申请号：US14975988

申请日：2015-12-21

申请人： Metabolon, Inc.

发明人： Yun Fu HU ,  Costel CHIRILA ,  Danny ALEXANDER ,  Michael MILBURN ,  Matthew W. MITCHELL ,  Walter GALL ,  Kay A. LAWTON

IPC分类号： G01N33/53 ,  G01N33/483

CPC分类号： G01N33/5308 ,  G01N33/483 ,  G01N33/487 ,  G01N33/5091 ,  G01N33/6893 ,  G01N2800/04 ,  G01N2800/042 ,  G01N2800/044 ,  G01N2800/32 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/56

摘要： Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy.

摘要翻译： 提供了与胰岛素抵抗，前期糖尿病，2型糖尿病，代谢综合征，动脉粥样硬化和心肌病有关的生物标志物，以及使用这样的生物标志物作为胰岛素抵抗，前期糖尿病，2型糖尿病，代谢综合征的生物标志物的方法 ，动脉粥样硬化和心肌病。 此外，还提供了用于调节受试者的各种病症或病症的方法。 还提供了小分子实体作为胰岛素抵抗，糖尿病前期，2型糖尿病，代谢综合征，动脉粥样硬化和心肌病的生物标志物的套件。

公开(公告)号：US20180203021A1

公开(公告)日：2018-07-19

申请号：US15872373

申请日：2018-01-16

申请人： Metabolon, Inc.

发明人： Walter GALL ,  Jeffery Edmond Cobb ,  Kirk Lane Pappan

IPC分类号： G01N33/68 ,  G01N33/53 ,  G16H50/30

CPC分类号： G01N33/6893 ,  G01N33/5308 ,  G01N2333/46 ,  G01N2800/042 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/60 ,  G16H50/30

摘要： Biomarkers relating to insulin resistance and insulin resistance-related disorders are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, dysglycemia, type-2 diabetes, and cardiovascular disease. In addition, methods for monitoring the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, dysglycemia, type-2 diabetes, and cardiovascular disease.

公开(公告)号：US20150362510A1

公开(公告)日：2015-12-17

申请号：US14763962

申请日：2014-01-16

申请人： METABOLON, INC.

发明人： Walter GALL ,  Jeffrey Edmond COBB ,  Kirk Lane PAPPAN

IPC分类号： G01N33/68 ,  G01N33/53

CPC分类号： G01N33/6893 ,  G01N33/5308 ,  G01N2333/46 ,  G01N2800/042 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/60 ,  G06F19/00 ,  G16H50/30

摘要： Biomarkers relating to insulin resistance and insulin resistance-related disorders are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, dysglycemia, type-2 diabetes, and cardiovascular disease. In addition, methods for monitoring the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, dysglycemia, type-2 diabetes, and cardiovascular disease.

摘要翻译： 提供了与胰岛素抵抗和胰岛素抵抗相关疾病相关的生物标志物，以及使用这些生物标志物作为胰岛素抵抗，血糖异常，2型糖尿病和心血管疾病的生物标志物的方法。 此外，还提供了用于监测受试者的各种疾病或病症的方法。 还提供了小分子实体的套件作为胰岛素抵抗，血糖异常，2型糖尿病和心血管疾病的生物标志物。