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公开(公告)号:US20090325264A1
公开(公告)日:2009-12-31
申请号:US12428820
申请日:2009-04-23
申请人: MICHAEL J. STOREK , HENRY E. VALENTIN , STEVEN E. SCREEN , VIRGINIA URSIN , BYRON FROMAN , KEVIN JARRELL , SARA A. SALVADOR , ROBERT MCCARROLL , PRASHANTH VISHWANATH
发明人: MICHAEL J. STOREK , HENRY E. VALENTIN , STEVEN E. SCREEN , VIRGINIA URSIN , BYRON FROMAN , KEVIN JARRELL , SARA A. SALVADOR , ROBERT MCCARROLL , PRASHANTH VISHWANATH
CPC分类号: C12N15/8247 , A23D9/00 , C12N9/0083
摘要: The present invention provides engineered fatty acid desaturase molecules preferring Gamma Linolenic Acid (GLA) over Linoleic Acid (LA) as a substrate. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds comprising the desaturase molecule, and methods for preparing and using the same. In particular, the disclosed engineered desaturase molecules are capable of altering the omega-3 fatty acid profiles in plants and plant parts.
摘要翻译: 本发明提供优选亚麻酸(GLA)以亚油酸(LA)为底物的工程化脂肪酸去饱和酶分子。 本发明还公开了组合物,多核苷酸构建体,转化的宿主细胞,转基因植物和包含去饱和酶分子的种子,以及其制备和使用该方法。 特别地,所公开的工程化去饱和酶分子能够改变植物和植物部分中的ω-3脂肪酸谱。