公开(公告)号：US11467093B2

公开(公告)日：2022-10-11

申请号：US16662462

申请日：2019-10-24

申请人： MING CHUAN UNIVERSITY

发明人： Yu-Cheng Lin

IPC分类号： G01N21/25 ,  G02B6/26 ,  G01N21/77 ,  C12Q1/6825 ,  G01N33/72

摘要： An electrical polarity adjustable biosensor based on lossy mode resonance includes a first polarity module, a second polarity module, and a plurality of spacers disposed between the first polarity module and the second polarity module. A biomaterial sensing region for injecting an object to be tested is formed between a bioprobe layer of the first polarity module and a second electrode layer of the second polarity module. An electric field is formed between a lossy mode resonance layer of the first polarity module and the second electrode layer, and the electric field acts on a plurality of bioprobes of the bioprobe layer and the object to be tested. The present disclosure further includes a method of using the electrical polarity adjustable biosensor based on lossy mode resonance.

公开(公告)号：US11692936B2

公开(公告)日：2023-07-04

申请号：US17308693

申请日：2021-05-05

申请人： MING CHUAN UNIVERSITY

发明人： Yu-Cheng Lin

IPC分类号： G01N21/25 ,  G01N21/552 ,  G02B6/122 ,  G01N21/77

CPC分类号： G01N21/553 ,  G01N21/7703 ,  G02B6/1226 ,  G01N2021/258

摘要： A biological sensing apparatus includes an optical waveguide substrate, a surface plasmon resonance (SPR) layer, and a lossy mode resonance (LMR) layer. The optical waveguide substrate includes a light input end and a light output end opposite to each other, and a biological sensing area is formed on one surface of the optical waveguide substrate between the light input end and the light output end. The SPR layer includes a metal layer and a plurality of biological probes. The metal layer is arranged on part of the biological sensing area, and the plurality of biological probes are evenly arranged on the metal layer. The LMR layer is arranged on part of the biological sensing area, and the LMR layer and the SPR layer are not overlapped. The present disclosure further includes a biological sensing system and a method of using the same.

公开(公告)号：US11630105B2

公开(公告)日：2023-04-18

申请号：US17736666

申请日：2022-05-04

申请人： MING CHUAN UNIVERSITY

发明人： Yu-Cheng Lin

IPC分类号： G01N33/543 ,  G01N21/552 ,  G01N21/77 ,  G01N21/03

摘要： A self-heating biosensor based on lossy mode resonance (LMR) includes a waveguide unit and a lossy mode resonance layer. The waveguide unit is a flat plate, including two planes and at least two sets of opposite sides. One set of the opposite sides of the waveguide unit has a light input end and a light output end. The lossy mode resonance layer is disposed on one of the planes of the waveguide unit. Two heating electrodes are formed at two positions of the lossy mode resonance layer, and the two positions are relevant to one set of the opposite sides of the waveguide unit. A biomaterial sensing region having bioprobes are formed between the two heating electrodes. The present disclosure further includes a using method relevant to the self-heating biosensor based on lossy mode resonance.