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公开(公告)号:US20230045844A1
公开(公告)日:2023-02-16
申请号:US17792099
申请日:2021-01-13
发明人: Tomokazu TAKAI , Hitoshi MIZUNO , Akira TAKAHASHI , Toshiya ENDO , Shinichi SAKAUE , Norimasa IWASAKI , Tomohiro ONODERA , Koji IWASAKI
IPC分类号: A61K31/734 , A61K9/06 , A61L27/20 , A61L27/52 , A61P19/04
摘要: Realized is reliable fixation of a material in a fluid state containing a monovalent metal salt of alginic acid when the material is applied to a subject. A combination of compositions comprising a first material composition containing a monovalent metal salt of alginic acid and a second material composition containing a cross-linking agent having an action of cross-linking the monovalent metal salt of alginic acid, wherein the combination is to be used in such a way as to apply the first material composition to a subject in a fluid state and contact the second material composition with the first material composition applied to the subject to gel at least a part of the first material composition, wherein the first material composition further contains a coloring component so that a formation state of a gel coat on a surface of the first material composition applied to the subject can be evaluated.