公开(公告)号：US11730748B2

公开(公告)日：2023-08-22

申请号：US17103391

申请日：2020-11-24

Applicant: MSD International GMBH

Inventor： Cyril B. Dousson ,  David Dukhan ,  Christophe C. Parsy ,  Stephane L. Bogen

IPC: A61K31/675 ,  A61P1/16 ,  A61P31/12 ,  C07F9/6558 ,  C07F9/6561

CPC classification number: A61K31/675 ,  A61P1/16 ,  C07F9/65586 ,  C07F9/65616

Abstract: The present invention relates to Compounds of Formula (I) or Formula (II):




or a pharmaceutically acceptable salt, solvate or enantiomer thereof, wherein A, B, R1, R2, R3, R4, Q and V are as defined herein. The present invention also relates to pharmaceutical compositions comprising a Compound of Formula (I) or Formula (II) and to their use in therapy.

公开(公告)号：US20210205339A1

公开(公告)日：2021-07-08

申请号：US17103391

申请日：2020-11-24

Applicant: MSD International GMBH

Inventor： Cyril B. Dousson ,  David Dukhan ,  Christophe C. Parsy ,  Stephane L. Bogen

IPC: A61K31/675 ,  A61P1/16 ,  C07F9/6558 ,  C07F9/6561

Abstract: The present invention relates to Compounds of Formula (I) or Formula (II): or a pharmaceutically acceptable salt, solvate or enantiomer thereof, wherein A, B, R1, R2, R3, R4, Q and V are as defined herein. The present invention also relates to pharmaceutical compositions comprising a Compound of Formula (I) or Formula (II) and to their use in therapy.