公开(公告)号：US10531957B2

公开(公告)日：2020-01-14

申请号：US15159406

申请日：2016-05-19

申请人： MUSCULOSKELETAL TRANSPLANT FOUNDATION

发明人： Michele McAllister ,  David Wang ,  Michelle Bubear ,  Joed Canales ,  Amy Chang ,  Roman Shikhanovich ,  Mark Spilker ,  Eric Semler

IPC分类号： A61F2/28 ,  A61L27/36

摘要： Surgical implants (or grafts) for the repair of bone defects, more particularly, surgical implants that include demineralized bone fibers, are disclosed. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration. Methods for making such implants and for increasing their wettability and ensuring uniform density are also disclosed.

公开(公告)号：US11596517B2

公开(公告)日：2023-03-07

申请号：US16598354

申请日：2019-10-10

申请人： Musculoskeletal Transplant Foundation

发明人： Michele McAllister ,  David Wang ,  Michelle Bubear ,  Joed Canales ,  Amy Chang ,  Roman Shikhanovich ,  Mark Spilker ,  Eric Semler

IPC分类号： A61F2/28 ,  A61L27/36

摘要： Methods for making surgical implants (or grafts) for the repair of bone defects, and more particularly, surgical implants that include demineralized bone fibers, are disclosed. Also disclosed are methods for increasing the wettability and ensuring uniform density of such implants. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration.

公开(公告)号：US20230030907A1

公开(公告)日：2023-02-02

申请号：US17966092

申请日：2022-10-14

申请人： Musculoskeletal Transplant Foundation

发明人： Michele Christine McAllister ,  David Wang ,  Michelle Bubear ,  Joed Canales ,  Amy Chang ,  Roman Shikhanovich ,  Mark Spilker ,  Eric Semler

IPC分类号： A61F2/28 ,  A61L27/36

摘要： Methods for making surgical implants (or grafts) for the repair of bone defects, and more particularly, surgical implants that include demineralized bone fibers, are disclosed. Also disclosed are methods for increasing the wettability and ensuring uniform density of such implants. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration.

公开(公告)号：US20200046501A1

公开(公告)日：2020-02-13

申请号：US16598354

申请日：2019-10-10

申请人： Musculoskeletal Transplant Foundation

发明人： Michele McAllister ,  David Wang ,  Michelle Bubear ,  Joed Canales ,  Amy Chang ,  Roman Shikhanovich ,  Mark Spilker ,  Eric Semler

IPC分类号： A61F2/28 ,  A61L27/36

摘要： Methods for making surgical implants (or grafts) for the repair of bone defects, and more particularly, surgical implants that include demineralized bone fibers, are disclosed. Also disclosed are methods for increasing the wettability and ensuring uniform density of such implants. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration.

公开(公告)号：US20160361171A1

公开(公告)日：2016-12-15

申请号：US15159406

申请日：2016-05-19

申请人： MUSCULOSKELETAL TRANSPLANT FOUNDATION

发明人： David Wang ,  Michele McAllister ,  Michelle Bubear ,  Joed Canales ,  Amy Chang ,  Roman Shikhanovich ,  Mark Spilker ,  Eric Semler

IPC分类号： A61F2/28 ,  A61L27/36

CPC分类号： A61F2/28 ,  A61F2240/001 ,  A61L27/3604 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3683 ,  A61L2400/18 ,  A61L2430/02 ,  A61L2430/38

摘要： Surgical grafts for the repair of bone defects, more particularly, surgical grafts that include demineralized bone fibers, are disclosed. Methods for making such grafts and for increasing their wettability and ensuring uniform density are also disclosed.

摘要翻译： 公开了用于修复骨缺损的手术移植物，更具体地，涉及包括软化骨纤维的手术移植物。 还公开了制备这种移植物并提高其润湿性并确保均匀密度的方法。