公开(公告)号：US20180059004A1

公开(公告)日：2018-03-01

申请号：US15565208

申请日：2016-04-11

Applicant: MyCartis NV

Inventor： Robin Muller ,  Jose De Gil ,  Raphael Tornay ,  Matthieu Gaillard

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/53 ,  B01L3/00

CPC classification number: G01N21/0303 ,  B01L3/502715 ,  B01L2200/025 ,  B01L2300/0654 ,  B01L2300/14 ,  B01L2300/1805 ,  G01N21/253 ,  G01N21/645 ,  G01N33/5302 ,  G01N2021/0389 ,  G01N2021/6482 ,  G01N2201/021

Abstract: An analysis system comprising a cartridge and an instrument being designed for operating the cartridge. The cartridge comprises a chamber sealed by a foil capable of protruding when the chamber is pressurized. The instrument comprises an analysis window and a detection portion designed for being crossed by a signal emitted from the chamber toward the instrument when the chamber is placed opposite the detection portion. The instrument further comprises docking means to place the chamber opposite the detection portion so that when the chamber is pressurized, the foil protrudes toward the detection portion. The analysis system is characterized in that it further comprises spacing means to ensure that, when the cartridge is docked on the instrument via the docking means and the chamber is pressurized, said spacing means ensure a gap between the foil and the detection portion.

公开(公告)号：US20150141281A1

公开(公告)日：2015-05-21

申请号：US14413314

申请日：2013-07-10

Applicant: MYCARTIS NV

Inventor： Raphael Tornay ,  Nicolas Demierre ,  Jose De Gil ,  Robin Muller ,  Didier Falconnet

IPC: G01N33/543

CPC classification number: G01N33/54313 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2400/086 ,  G01N33/54366 ,  G01N33/54373 ,  Y10T436/2575

Abstract: The present invention relates to a method for performing a chemical and/or a biological assay comprising the following successive steps of: a) providing an assay device with a microchannel having an inlet and an outlet and further comprising restricting means designed to restrict the movement toward the outlet of microparticles introduced in the microchannel while letting a fluid to flow through the restricting means, b) introducing microparticles in the microchannel via the inlet, c) restricting the movement of said microparticles in the microchannel toward the outlet using restricting means, d) flowing a fluid sample through the microchannel, e) performing a biological and/or chemical read-out on each microparticle, the method further comprising the steps of: f) moving the microparticles in the microchannel, and g) repeating successively the steps d) and e).

Abstract translation: 本发明涉及一种用于进行化学和/或生物测定的方法，包括以下连续步骤：a）提供具有入口和出口的微通道的测定装置，并且还包括限制装置， 在使流体流过所述限制装置的同时引入微通道的出口，b）通过所述入口将微粒引入所述微通道中，c）使用限制装置限制所述微通道中所述微粒向所述出口的移动; d） 流体样品通过微通道，e）对每个微粒进行生物和/或化学读出，所述方法还包括以下步骤：f）移动微通道中的微粒，并且g）连续重复步骤d） 和e）。

公开(公告)号：US09625455B2

公开(公告)日：2017-04-18

申请号：US14413314

申请日：2013-07-10

Applicant: MYCARTIS NV

Inventor： Raphael Tornay ,  Nicolas Demierre ,  Jose De Gil ,  Robin Muller ,  Didier Falconnet

IPC: G01N33/543 ,  B01L3/00

CPC classification number: G01N33/54313 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2400/086 ,  G01N33/54366 ,  G01N33/54373 ,  Y10T436/2575

Abstract: A method for performing a chemical and/or a biological assay including the following successive steps of: a) providing an assay device with a microchannel having an inlet and an outlet and restricting means for restricting movement toward the outlet of microparticles introduced in the microchannel while letting a fluid to flow through the restricting means, b) introducing microparticles in the microchannel via the inlet, c) restricting the movement of said microparticles in the microchannel toward the outlet using the restricting means, d) flowing a fluid sample through the microchannel, and e) performing a biological and/or chemical read-out on each microparticle. The method also includes the steps of: f) moving the microparticles in the microchannel, and g) repeating successively the steps d) and e).