公开(公告)号：US20220088055A1

公开(公告)日：2022-03-24

申请号：US17094903

申请日：2020-11-11

Applicant: Macau University of Science and Technology

Inventor： Zhi-Hong Jiang ,  Lee-Fong Yau ,  Tian-Tian Tong ,  Hao Huang ,  Kua Hu ,  Elaine Lai-Han Leung

IPC: A61K31/7105 ,  A61P35/00 ,  A61K31/713 ,  C07K16/28

Abstract: This invention discloses a medicinal composition includes a non-coding RNA molecule and an antibody targeting a tumor antigen for preventing and/or treating cancer. This invention uses the synergistic combination of a non-coding RNA molecule or its functional variant or homologue, and an antibody targeting a tumor antigen to prevent and/or treat cancer, thereby providing a novel and effective method in preventing and/or treating various cancers.

公开(公告)号：US10900966B2

公开(公告)日：2021-01-26

申请号：US16281122

申请日：2019-02-21

Applicant: Macau University of Science and Technology

Inventor： Liang Liu ,  Jing-Rong Wang ,  Weina Gao ,  Leefong Yau ,  Hao Huang ,  Qiong Meng ,  Tiantian Tong ,  Zhi-Hong Jiang

IPC: G01N33/564 ,  G01N33/48 ,  G01N1/40 ,  G01N30/08 ,  G01N30/60 ,  B01L3/00 ,  G01N30/72 ,  G01N30/88

Abstract: The present invention discloses a method of determining the presence of autoimmune disease with the use of glycan biomarkers. A method of improving the detection sensitivity of trace glycans from a mixture of glycans and a microfluidic chip therefor are also disclosed.

公开(公告)号：US10234454B2

公开(公告)日：2019-03-19

申请号：US14883622

申请日：2015-10-15

Applicant: Macau University of Science and Technology

Inventor： Liang Liu ,  Jing-Rong Wang ,  Weina Gao ,  Leefong Yau ,  Hao Huang ,  Qiong Meng ,  Tiantian Tong ,  Zhi-Hong Jiang

IPC: G01N33/564 ,  G01N33/48 ,  G01N30/08 ,  B01L3/00 ,  G01N1/40 ,  G01N30/60 ,  G01N30/72 ,  G01N30/88

Abstract: The present invention discloses a method of determining the presence of autoimmune disease with the use of glycan biomarkers. A method of improving the detection sensitivity of trace glycans from a mixture of glycans and a microfluidic chip therefor are also disclosed.

公开(公告)号：US11944636B2

公开(公告)日：2024-04-02

申请号：US17094903

申请日：2020-11-11

Applicant: Macau University of Science and Technology

Inventor： Zhi-Hong Jiang ,  Lee-Fong Yau ,  Tian-Tian Tong ,  Hao Huang ,  Kua Hu ,  Elaine Lai-Han Leung

IPC: C07H21/04 ,  A61K31/7105 ,  A61K31/713 ,  A61P35/00 ,  C07K16/28

CPC classification number: A61K31/7105 ,  A61K31/713 ,  A61P35/00 ,  C07K16/2818

Abstract: This invention discloses a medicinal composition includes a non-coding RNA molecule and an antibody targeting a tumor antigen for preventing and/or treating cancer. This invention uses the synergistic combination of a non-coding RNA molecule or its functional variant or homologue, and an antibody targeting a tumor antigen to prevent and/or treat cancer, thereby providing a novel and effective method in preventing and/or treating various cancers.