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公开(公告)号:US20090117103A1
公开(公告)日:2009-05-07
申请号:US11817947
申请日:2006-03-02
IPC分类号: A61K39/395 , C07K1/16 , A61P37/04
CPC分类号: C07K16/243 , B01D15/1871 , B01D15/361 , B01D15/3804 , C07K2317/56 , C07K2317/567 , C07K2319/00 , G01N30/461
摘要: The present invention provides for compositions of anti-M-CSF antibodies that are substantially free of endotoxin. Also provided are methods of treating M-CSF-mediated disorders with pharmaceutical formulations of anti-M-CSF antibodies having reduced endotoxin levels, including inflammatory diseases and neoplasia disorders.
摘要翻译: 本发明提供基本上不含内毒素的抗M-CSF抗体的组合物。 还提供了使用具有降低的内毒素水平的抗M-CSF抗体的药物制剂治疗M-CSF介导的病症的方法,包括炎症性疾病和瘤形成障碍。