公开(公告)号：US07850618B2

公开(公告)日：2010-12-14

申请号：US12008349

申请日：2008-01-10

申请人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger

发明人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger

IPC分类号： A61B5/08

CPC分类号： A61B5/4818 ,  A61B5/08 ,  A61B8/08

摘要： The present invention relates to a method of determining characteristics of biological tissues in humans and animals. In particular, it relates to determining the characteristics of tissues such as the lungs and airways by introducing a sound to the tissue, and recording the sound. The invention further includes an apparatus capable of such measurement. In a first aspect of the present invention there is provided a method of determining characteristics of biological tissue in situ, including: introducing a sound to the tissue at first position; detecting the sound at another position spaced from the first position after it has traveled through the tissue; calculating the velocity and attenuation of sound that has traveled through the tissue from the first position to another position; and correlating the velocity and attenuation of the detected sound to characteristics of the biological tissue.

摘要翻译： 本发明涉及一种确定人和动物生物组织特征的方法。 特别涉及通过向组织引入声音并记录声音来确定诸如肺和气道的组织的特征。 本发明还包括能够进行这种测量的装置。 在本发明的第一方面，提供了一种确定生物组织的特征的方法，包括：在第一位置向所述组织引入声音; 在其已经穿过组织后检测与第一位置间隔开的另一位置处的声音; 计算已经穿过组织从第一位置到另一位置的声音的速度和衰减; 并将检测到的声音的速度和衰减与生物组织的特征相关联。

公开(公告)号：US07708697B2

公开(公告)日：2010-05-04

申请号：US11107999

申请日：2005-04-15

申请人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger ,  Peter Camilleri ,  Jacqueline Anne Wilson ,  Frank Samuhel

发明人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger ,  Peter Camilleri ,  Jacqueline Anne Wilson ,  Frank Samuhel

IPC分类号： A61B5/08

CPC分类号： A61B5/085 ,  A61B5/08 ,  A61B5/4818 ,  A61B5/7257 ,  A61B8/08 ,  A61M16/0006 ,  A61M16/0051 ,  A61M16/026 ,  A61M16/0666 ,  A61M2016/0039 ,  A61M2230/04 ,  A61M2230/205 ,  A61M2230/65

摘要： Airway monitoring apparatus 30 includes a driver 6 for applying sound in the audible frequency range to the airway of a subject and a detector 7 for monitoring the response of the airway, e.g. by detecting transmitted sound signal components and/or reflected sound signal components. Variations in the detected sound signal, e.g. energy, due to attenuation of the signal, give an indication of the state of the airway, e.g. airway patency, and can be used to monitor sleep-disordered breathing events, such as apnea and hypopnea, and to provide a breathing event index, e.g. AHI. The apparatus may provide servo-control for a respiratory assist device, such as a positive airway pressure device, so as to provide an appropriate pressure level setting. It may allow for home use of such devices and for home titration. It may also assist in discriminating central and obstructive breathing events, and in providing a measure of airway resistance.

摘要翻译： 气道监测装置30包括用于将可听频率范围内的声音施加到被检体的气道的驱动器6和用于监测气道的反应的检测器7，例如， 通过检测发送的声音信号分量和/或反射的声音信号分量。 检测到的声音信号的变化，例如， 能量，由于信号的衰减，给出气道状态的指示，例如。 气道通畅，并且可以用于监测睡眠呼吸障碍的呼吸事件，例如呼吸暂停和呼吸不足，并提供呼吸事件指数，例如呼吸道呼吸。 AHI。 该装置可以为诸如正气道压力装置的呼吸辅助装置提供伺服控制，以便提供适当的压力水平设置。 它可以允许家用这种装置和家庭滴定。 它也可以帮助区分中枢和阻塞性呼吸事件，并提供气道阻力的量度。

公开(公告)号：US20080154145A1

公开(公告)日：2008-06-26

申请号：US12008349

申请日：2008-01-10

申请人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger

发明人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger

IPC分类号： A61B5/08

CPC分类号： A61B5/4818 ,  A61B5/08 ,  A61B8/08

摘要： The present invention relates to a method of determining characteristics of biological tissues in humans and animals. In particular, it relates to determining the characteristics of tissues such as the lungs and airways by introducing a sound to the tissue, and recording the sound. The invention further includes an apparatus capable of such measurement. In a first aspect of the present invention there is provided a method of determining characteristics of biological tissue in situ, including: introducing a sound to the tissue at first position; detecting the sound at another position spaced from the first position after it has traveled through the tissue; calculating the velocity and attenuation of sound that has traveled through the tissue from the first position to another position; and correlating the velocity and attenuation of the detected sound to characteristics of the biological tissue.

摘要翻译： 本发明涉及一种确定人和动物生物组织特征的方法。 特别涉及通过向组织引入声音并记录声音来确定诸如肺和气道的组织的特征。 本发明还包括能够进行这种测量的装置。 在本发明的第一方面，提供了一种确定生物组织的特征的方法，包括：在第一位置向所述组织引入声音; 在其已经穿过组织后检测与第一位置间隔开的另一位置处的声音; 计算已经穿过组织从第一位置到另一位置的声音的速度和衰减; 并将检测到的声音的速度和衰减与生物组织的特征相关联。

公开(公告)号：US07347824B2

公开(公告)日：2008-03-25

申请号：US10272494

申请日：2002-10-15

申请人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger

发明人： Malcolm Howard Wilkinson ,  Clive Andrew Ramsden ,  Philip John Berger

IPC分类号： A61B5/08

CPC分类号： A61B5/4818 ,  A61B5/08 ,  A61B8/08

摘要： The present invention relates to a method of determining characteristics of biological tissues in humans and animals. In particular, it relates to determining the characteristics of tissues such as the lungs and airways by introducing a sound to the tissue, and recording the sound. The invention further includes an apparatus capable of such measurement. In a first aspect of the present invention there is provided a method of determining characteristics of biological tissue in situ, including: introducing a sound to the tissue at first position; detecting the sound at another position spaced from the first position after it has traveled through the tissue; calculating the velocity and attenuation of sound that has traveled through the tissue from the first position to another position; and correlating the velocity and attenuation of the detected sound to characteristics of the biological tissue.