专利检索 ap:("Malcolm Ward" OR "Helen Byers" OR "Brian Henry Anderton" OR "Pascal Derkinderen" OR "Christopher Hugh Reynolds" OR "Ritchie Williamson") AND inv:"Brian Henry Anderton" 第 1 页

1.

发明授权
Method of screening for inhibitors of tau protein phosphororylation by tyrosine kinase c-Abl 有权
标题翻译：筛选酪氨酸激酶c-Abl的tau蛋白磷酸化抑制剂的方法

公开(公告)号：US08367360B2

公开(公告)日：2013-02-05

申请号：US11630720

申请日：2005-06-21

申请人： Malcolm Ward , Helen Byers , Brian Henry Anderton , Pascal Derkinderen , Christopher Hugh Reynolds , Ritchie Williamson

发明人： Malcolm Ward , Helen Byers , Brian Henry Anderton , Pascal Derkinderen , Christopher Hugh Reynolds , Ritchie Williamson

IPC分类号： C12Q1/48

CPC分类号： C12Q1/485 , A61K33/40 , G01N33/6896 , G01N2333/912 , G01N2333/9121 , G01N2440/14 , G01N2500/02

摘要： The present invention provides methods of screening for candidate compounds useful in the treatment of Alzheimer's disease and related conditions by inhibiting specific phosphorylation of tau protein by tyrosine kinase c-Abl.

摘要翻译： 本发明提供了通过酪氨酸激酶c-Ab1抑制tau蛋白的特异性磷酸化来筛选可用于治疗阿尔茨海默病和相关病症的候选化合物的方法。