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公开(公告)号：US20100266514A9
公开(公告)日：2010-10-21
申请号：US12042870
申请日：2008-03-05
IPC分类号： A61K8/66
CPC分类号： A61Q11/00 , A61K8/66 , A61K2800/88
摘要： A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an ionic surfactant such as sodium lauryl sulfate, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth whereby enzyme activity is maintained with improved dentifrice foaming characteristics.
摘要翻译： 公开了一种双组分脱敏洁牙剂组合物，其包含含有酶如木瓜蛋白酶的第一洁齿剂组分和含有离子表面活性剂如十二烷基硫酸钠的第二洁齿剂组分，第一和第二洁齿剂组分彼此分离直到分配 应用于牙齿，由此保持酶活性并提高洁牙剂发泡特性。
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2.发明申请ANTIBACTERIAL DENTIFRICE EXHIBITING ENHANCED ANTIPLAQUE AND BREATH FRESHENING PROPERTIES 审中-公开抗菌素抗生素和抗生素的抗菌性能公开(公告)号：US20120141388A1
公开(公告)日：2012-06-07
申请号：US13372871
申请日：2012-02-14
申请人： Lori H. Szeles , Xiaoyan Liu , Malcolm Williams , M. Teresa R. Carale , Michael Prencipe , James G. Masters
发明人： Lori H. Szeles , Xiaoyan Liu , Malcolm Williams , M. Teresa R. Carale , Michael Prencipe , James G. Masters
摘要： An abrasive dentifrice composition which effects enhanced antiplaque and breath freshening properties which comprises an orally acceptable vehicle containing a combination of a safe and effective amount of an antibacterial agent and at least two enzyme ingredients.
摘要翻译： 一种具有增强的抗牙斑和呼吸清新性能的研磨性洁齿剂组合物，其包含含有安全有效量的抗菌剂和至少两种酶成分的组合的口服可接受的载体。
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3.发明授权Antibacterial dentifrice exhibiting enhanced antiplaque and breath freshening properties 失效抗菌洁齿剂具有增强的抗牙斑和呼吸清新性能公开(公告)号：US08128911B2
公开(公告)日：2012-03-06
申请号：US10143388
申请日：2002-05-10
申请人： Lori H. Szeles , Xiaoyan Liu , Malcolm Williams , M. Teresa R. Carale , Michael Prencipe , James G. Masters
发明人： Lori H. Szeles , Xiaoyan Liu , Malcolm Williams , M. Teresa R. Carale , Michael Prencipe , James G. Masters
摘要： An abrasive dentifrice composition which effects enhanced antiplaque and breath freshening properties which comprises an orally acceptable vehicle containing a combination of a safe and effective amount of an antibacterial agent and at least two enzyme ingredients.
摘要翻译： 一种具有增强的抗牙斑和呼吸清新性能的研磨性洁齿剂组合物，其包含含有安全有效量的抗菌剂和至少两种酶成分的组合的口服可接受的载体。
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公开(公告)号：US20080152601A1
公开(公告)日：2008-06-26
申请号：US12042870
申请日：2008-03-05
IPC分类号： A61K8/66
CPC分类号： A61Q11/00 , A61K8/66 , A61K2800/88
摘要： A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an ionic surfactant such as sodium lauryl sulfate, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth whereby enzyme activity is maintained with improved dentifrice foaming characteristics.
摘要翻译： 公开了一种双组分脱敏洁牙剂组合物，其包含含有酶如木瓜蛋白酶的第一洁齿剂组分和含有离子表面活性剂如十二烷基硫酸钠的第二洁齿剂组分，第一和第二洁齿剂组分彼此分离直到分配 应用于牙齿，由此保持酶活性并提高洁牙剂发泡特性。
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公开(公告)号：US06927053B2
公开(公告)日：2005-08-09
申请号：US10229551
申请日：2002-08-28
CPC分类号： A61Q11/00 , A61K8/66 , A61K2800/88
摘要： A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an ionic surfactant such as sodium lauryl sulfate, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth whereby enzyme activity is maintained with improved dentifrice foaming characteristics.
摘要翻译： 公开了一种双组分脱敏洁牙剂组合物，其包含含有酶如木瓜蛋白酶的第一洁齿剂组分和含有离子表面活性剂如十二烷基硫酸钠的第二洁齿剂组分，第一和第二洁齿剂组分彼此分离直到分配 应用于牙齿，由此保持酶活性并提高洁牙剂发泡特性。
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公开(公告)号：US06379654B1
公开(公告)日：2002-04-30
申请号：US09698453
申请日：2000-10-27
IPC分类号： A61K728
CPC分类号： A61Q11/00 , A61K8/25 , A61K8/66 , A61K38/4873
摘要： An abrasive dentifrice composition which effects enhanced tooth and stain removal which comprises an orally acceptable vehicle containing a combination of a low oil absorption silica abrasive having an oil absorption value of less than 100 cc/100 g silica and an proteolytic enzyme.
摘要翻译： 一种具有增强的牙齿和污迹去除效果的研磨性洁齿剂组合物，其包含含有油吸收值小于100cc / 100g硅胶的低吸油性二氧化硅磨料与蛋白水解酶的组合的口腔可接受的载体。
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7.发明授权Dentifrice composition containing calcium peroxide having heightened tooth whitening effect 失效含有过氧化钙的牙粉组合物具有高牙齿美白效果
公开(公告)号：US5698182A
公开(公告)日：1997-12-16
申请号：US735163
申请日：1996-10-22
摘要： A method for inhibiting dental calculus concomitant with tooth whitening is disclosed wherein there is applied to the teeth an oral composition containing in a vehicle an amount of a anticalculus phosphate salt and an amount of calcium peroxide effective to whiten teeth, the vehicle containing about 4 to about 9% by weight water and an amount of calcined alumina effective to heighten the whitening effect of the CaO2, and allowing the composition to remain on the teeth for a time sufficient to effect whitening thereof.
摘要翻译： 公开了一种与牙齿美白同时抑制牙结石的方法，其中向牙齿施用含有载体中的一种口服抗微凝胶磷酸盐和一种有效增白牙齿的量的过氧化钙，该载体含有约4至 约9重量％的水和一定量的煅烧氧化铝有效地提高了CaO 2的增白效果，并使组合物保留在牙齿上足以实现其美白的时间。
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公开(公告)号：US06652841B1
公开(公告)日：2003-11-25
申请号：US10229622
申请日：2002-08-28
IPC分类号： A61K716
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/66 , A61K2800/88
摘要： A two component antiplaque dentifrice composition is disclosed which comprises first and second dentifrice components containing an enzyme such as papain and a metal salt such as stannous fluoride, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth.
摘要翻译： 公开了一种双组分抗牙垢洁牙剂组合物，其包含含有酶如木瓜蛋白酶和金属盐如氟化亚锡的第一和第二洁齿剂组分，第一和第二洁齿剂组分彼此分开直到分配用于施用于牙齿。
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9.发明授权
公开(公告)号：US5601803A
公开(公告)日：1997-02-11
申请号：US451289
申请日：1995-05-26
IPC分类号： A61K8/92 , A61K8/21 , A61K8/25 , A61K8/29 , A61K8/34 , A61K8/36 , A61K8/40 , A61K8/60 , A61K8/72 , A61K8/73 , A61Q11/00 , A61K7/16 , A61K7/18
CPC分类号： A61K8/731 , A61K8/25 , A61Q11/00 , A61K2800/412 , A61K2800/5422 , A61K2800/5424
摘要： There is disclosed a flavored silica abrasive dentifrice which delivers higher levels and intensity of flavor and exhibits less stringiness the dentifrice having incorporated therein a cellulose gel comprised of a coprocessed mixture of microcrystalline cellulose and a cellulose gum such as carboxymethylcellulose.
摘要翻译： 公开了一种风味二氧化硅研磨剂，其具有更高水平和强度的风味，并且具有较少的拉丝性，其中掺入了由微晶纤维素和纤维素胶如羧甲基纤维素的共加工混合物组成的纤维素凝胶。
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公开(公告)号：US06375933B1
公开(公告)日：2002-04-23
申请号：US09753854
申请日：2001-01-03
申请人： Ravi Subramanyam , Malcolm Williams , Petros Gebreselassie , Xiaoyan Liu , Angelo Zaccagnino , James G. Masters
发明人： Ravi Subramanyam , Malcolm Williams , Petros Gebreselassie , Xiaoyan Liu , Angelo Zaccagnino , James G. Masters
IPC分类号： A61K716
CPC分类号： A61Q15/00 , A61K8/20 , A61K8/27 , A61K2800/88 , A61Q11/00
摘要： A dual component oral composition to suppress oral malodor and provide long lasting breath protection in the oral cavity which comprises a first dentifrice component having a substantially neutral pH and containing a zinc ion releasable compound and a chlorite ion releasable compound, the second dentifrice component having an acid pH, the first and second components being maintained separate from each other until dispensed and combined for application to teeth, the combined components having a pH of no greater than 7.
摘要翻译： 一种双组分口服组合物，用于抑制口腔恶臭并在口腔中提供持久的呼吸保护，其包含具有基本上中性的pH并含有锌离子可释放化合物和亚氯酸盐离子可释放化合物的第一洁齿剂组分，所述第二洁齿剂组分具有 酸性pH值，第一和第二组分保持彼此分离直到分配并组合以施用于牙齿，组合的组分具有不大于7的pH。
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