-
公开(公告)号：US09708371B2
公开(公告)日：2017-07-18
申请号：US14239178
申请日：2012-08-17
CPC分类号： C07K7/08 , A61K38/10 , A61K38/12 , A61K45/06 , C07K5/02 , C07K7/54 , C11D3/3436 , G01N2800/065 , Y02A50/414
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
-
公开(公告)号：US20150094272A1
公开(公告)日：2015-04-02
申请号：US14239178
申请日：2012-08-17
CPC分类号： C07K7/08 , A61K38/10 , A61K38/12 , A61K45/06 , C07K5/02 , C07K7/54 , C11D3/3436 , G01N2800/065 , Y02A50/414
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
摘要翻译： 本发明涉及用于治疗胃肠道疾病和病症的肽，组合物和相关方法，包括但不限于肠易激综合征（IBS），胃肠蠕动障碍，功能性胃肠道疾病，胃食管反流病（GERD），十二指肠胃反流，克罗恩氏病 疾病，溃疡性结肠炎，炎性肠病，功能性胃灼热，消化不良，内脏痛，胃轻瘫，慢性肠假性梗阻（或结肠假性梗阻），与便秘相关的病症和病症以及其它病症和病症在本文中用肽描述 和激活鸟苷酸环化酶C（GC-C）受体的其它试剂。
-
公开(公告)号：US08933030B2
公开(公告)日：2015-01-13
申请号：US13579685
申请日：2011-02-17
申请人： Angelika Fretzen , Hong Zhao , Marco Kessler
发明人： Angelika Fretzen , Hong Zhao , Marco Kessler
IPC分类号： A61K38/00 , A61P1/04 , A61K38/12 , A61K38/04 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , C07K7/08 , A61K38/10 , A61K45/06
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
摘要翻译： 本发明涉及用于治疗胃肠道疾病和病症的肽，组合物和相关方法，包括但不限于肠易激综合征（IBS），胃肠蠕动障碍，功能性胃肠道疾病，胃食管反流病（GERD），十二指肠胃反流，克罗恩氏病 疾病，溃疡性结肠炎，炎性肠病，功能性胃灼热，消化不良，内脏痛，胃轻瘫，慢性肠假性梗阻（或结肠假性梗阻），与便秘相关的病症和病症以及其它病症和病症在本文中用肽描述 和激活鸟苷酸环化酶C（GC-C）受体的其它试剂。
-
公开(公告)号：US20140073571A9
公开(公告)日：2014-03-13
申请号：US13579685
申请日：2011-02-17
申请人： Angelika Fretzen , Hong Zhao , Marco Kessler
发明人： Angelika Fretzen , Hong Zhao , Marco Kessler
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
摘要翻译： 本发明涉及用于治疗胃肠道疾病和病症的肽，组合物和相关方法，包括但不限于肠易激综合征（IBS），胃肠蠕动障碍，功能性胃肠道疾病，胃食管反流病（GERD），十二指肠胃反流，克罗恩氏病 疾病，溃疡性结肠炎，炎性肠病，功能性胃灼热，消化不良，内脏痛，胃轻瘫，慢性肠假性梗阻（或结肠假性梗阻），与便秘相关的病症和病症以及其它病症和病症在本文中用肽描述 和激活鸟苷酸环化酶C（GC-C）受体的其它试剂。
-
公开(公告)号：US20130190238A1
公开(公告)日：2013-07-25
申请号：US13579685
申请日：2011-02-17
申请人： Angelika Fretzen , Hong Zhao , Marco Kessler
发明人： Angelika Fretzen , Hong Zhao , Marco Kessler
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
-
公开(公告)号：US20140179607A9
公开(公告)日：2014-06-26
申请号：US13508843
申请日：2010-11-09
CPC分类号： A61K38/10 , A61K38/00 , A61K45/06 , C07K7/08 , C07K14/4702
摘要： The present invention provides peptides that are useful for the treatment of gastrointestinal disorders. The present invention also provides compositions and methods of treating gastrointestinal disorders and pharmaceutical compositions for accomplishing the same. In some embodiments, these pharmaceutical compositions include oral dosage forms.
摘要翻译： 本发明提供可用于治疗胃肠道疾病的肽。 本发明还提供治疗胃肠疾病的组合物和方法以及用于实现其的药物组合物。 在一些实施方案中，这些药物组合物包括口服剂型。
-
公开(公告)号：US08507447B2
公开(公告)日：2013-08-13
申请号：US12942887
申请日：2010-11-09
IPC分类号： A61K38/10
CPC分类号： A61K38/10 , A61K38/00 , A61K45/06 , C07K7/08 , C07K14/4702
摘要： The present invention provides peptides that are useful for the treatment of gastrointestinal disorders. The present invention also provides compositions and methods of treating gastrointestinal disorders and pharmaceutical compositions for accomplishing the same. In some embodiments, these pharmaceutical compositions include oral dosage forms.
摘要翻译： 本发明提供可用于治疗胃肠道疾病的肽。 本发明还提供治疗胃肠疾病的组合物和方法以及用于实现其的药物组合物。 在一些实施方案中，这些药物组合物包括口服剂型。
-
公开(公告)号：US09650417B2
公开(公告)日：2017-05-16
申请号：US14116864
申请日：2012-05-11
摘要： The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including irritable bowel syndrome and constipation.
-
公开(公告)号：US09527887B2
公开(公告)日：2016-12-27
申请号：US14124282
申请日：2012-06-08
摘要： The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including irritable bowel syndrome and constipation.
摘要翻译： 本发明提供了治疗较低胃肠道疾病（包括肠易激综合征和便秘）的药物组合物和方法。
-
公开(公告)号：US08735360B2
公开(公告)日：2014-05-27
申请号：US13514158
申请日：2010-12-07
CPC分类号： C07K7/08 , A61K9/0019 , A61K38/00 , A61K38/10 , A61K45/06
摘要： Described herein are peptides, compositions, and related methods for treating upper gastrointestinal disorders and conditions (e.g., dyspepsia, gastroparesis, post-operative gastric ileus, a functional esophageal disorder, a functional gastroduodenal disorder, gastroesophageal reflux disease (GERD), or a duodenal or stomach ulcer) as well as other conditions and disorders that are described herein.
摘要翻译： 本文描述了用于治疗上消化道疾病和病症（例如，消化不良，胃轻瘫，术后胃肠梗阻，功能性食管障碍，功能性胃十二指肠疾病，胃食管反流病（GERD）或十二指肠癌）的肽，组合物和相关方法 或胃溃疡）以及本文所述的其它病症和障碍。
-
-
-
-
-
-
-
-
-
搜索结果
40 条记录 (耗时 0.028 秒)
