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公开(公告)号：US20230227552A1
公开(公告)日：2023-07-20
申请号：US17855332
申请日：2022-06-30
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew , Madan Katragadda , Peter Marek , Gurkan Guntas
CPC分类号： C07K16/2809 , A61P37/04 , A61P35/00 , C07K2317/565 , C07K2317/52
摘要： The disclosure provides antibody molecules that bind to TCR VP regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US11845797B2
公开(公告)日：2023-12-19
申请号：US17256917
申请日：2019-07-03
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
CPC分类号： C07K16/2809 , A61K35/17 , A61P35/00 , C07K16/2803 , C07K16/283 , C07K16/2878 , C12N5/0634 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/55 , C07K2317/622 , C07K2317/92
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US20240076377A1
公开(公告)日：2024-03-07
申请号：US18472920
申请日：2023-09-22
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
CPC分类号： C07K16/2809 , A61K35/17 , A61P35/00 , C07K16/2803 , C07K16/283 , C07K16/2878 , C12N5/0634 , A61K2039/505
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US20230142522A1
公开(公告)日：2023-05-11
申请号：US17820811
申请日：2022-08-18
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
CPC分类号： C07K16/2809 , A61P35/00 , A61K35/17 , C07K16/2803 , C07K16/283 , C07K16/2878 , C12N5/0634 , A61K2039/505
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US20230025484A1
公开(公告)日：2023-01-26
申请号：US17820634
申请日：2022-08-18
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US11965025B2
公开(公告)日：2024-04-23
申请号：US17820794
申请日：2022-08-18
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
CPC分类号： C07K16/2809 , A61K35/17 , A61P35/00 , C07K16/2803 , C07K16/283 , C07K16/2878 , C12N5/0634 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/55 , C07K2317/622 , C07K2317/92
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US20230031734A1
公开(公告)日：2023-02-02
申请号：US17820818
申请日：2022-08-18
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US20220064297A1
公开(公告)日：2022-03-03
申请号：US17529017
申请日：2021-11-17
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US20240301060A1
公开(公告)日：2024-09-12
申请号：US18431634
申请日：2024-02-02
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew
CPC分类号： C07K16/2809 , A61K35/17 , A61P35/00 , C07K16/2803 , C07K16/283 , C07K16/2878 , C12N5/0634 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/55 , C07K2317/622 , C07K2317/92
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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公开(公告)号：US20230374133A1
公开(公告)日：2023-11-23
申请号：US18341688
申请日：2023-06-26
发明人： Seng-Lai Tan , Brian Edward Vash , Jonathan Hsu , Dilini Charmain Gunasekera , Sangeetha Sagar Palakurthi , Andreas Loew , Madan Katragadda , Peter Marek , Gurkan Guntas
CPC分类号： C07K16/2809 , A61P37/04 , A61P35/00 , C07K2317/52 , C07K2317/565
摘要： The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
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