专利检索 ap:("Margaret Phillips" OR "Pradipsinh Rathod" OR "Jeffery Baldwin" OR "Ramesh Gujjar") AND inv:"Jeffery Baldwin" 第 1 页

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发明申请
DIHYDROOROTATE DEHYDROGENASE INHIBITORS WITH SELECTIVE ANTI-MALARIAL ACTIVITY 审中-公开
标题翻译：具有选择性疟疾活性的DIHYDROOROTATE DEHYDROGENASE抑制剂

公开(公告)号：US20080027079A1

公开(公告)日：2008-01-31

申请号：US11758137

申请日：2007-06-05

申请人： Margaret Phillips , Pradipsinh Rathod , Jeffery Baldwin , Ramesh Gujjar

发明人： Margaret Phillips , Pradipsinh Rathod , Jeffery Baldwin , Ramesh Gujjar

IPC分类号： A61K31/519 , A61P43/00

CPC分类号： C07D487/04

摘要： Pharmaceutical compositions comprising compounds of the formula where R1, R2, and R3 are described here, have therapeutic utility in selectively inhibiting P. falciparum dihydroorotate dehydrogenase. Accordingly, such compositions have use in the treatment and prevention of malaria.

摘要翻译： 包含下式化合物的药物组合物，其中R 1，R 2，R 3和R 3 3在此描述，具有选择性抑制P的作用。恶性疟原虫二氢乳清酸脱氢酶。因此，这些组合物可用于治疗和预防疟疾。