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    Loop module for tufting machine
    4.
    发明授权
    Loop module for tufting machine 失效
    簇绒机的回路模块

    公开(公告)号：US06431097B1

    公开(公告)日：2002-08-13

    申请号：US09719717

    申请日：2000-12-15

    申请人： Warren John Meade ,  Angela Margaret Phillips ,  Jonathan William Clarke

    发明人： Warren John Meade ,  Angela Margaret Phillips ,  Jonathan William Clarke

    IPC分类号： D05C1522

    CPC分类号： D05C15/22

    摘要： Loop pile hook module for use in a tufting machine, the module has a body member including a plurality of tufting machine hooks therein in side-by-side relationship, the hooks being formed from cylindrical, or other profile, pins which protrude from the body member to form a beak of the hooks.

    摘要翻译： 用于簇绒机的回卷桩模块，该模块具有主体部件，该主体部件具有并排关系的多个簇绒机钩，该钩部由圆柱形或其他轮廓形成，该销从主体突出 成员形成一个喙的钩子。

    Tufting needle with offset stem
    7.
    发明授权
    Tufting needle with offset stem 有权
    带偏心茎的针刺针

    公开(公告)号：US6062151A

    公开(公告)日：2000-05-16

    申请号：US150073

    申请日：1998-09-09

    申请人： Warren John Meade ,  Angela Margaret Phillips ,  Joan Emma Harneiss

    发明人： Warren John Meade ,  Angela Margaret Phillips ,  Joan Emma Harneiss

    IPC分类号： D05C15/20 ,  D05C15/04 ,  D05B85/10

    CPC分类号： D05C15/20

    摘要： A tufting needle is disclosed. The needle has a shank (1) and a stem (2). The needle has a lower eye (4) in the stem (2) which is close to the tip (3) and an upper eye (6 in FIG. 1, and 15 in FIG. 2), and a thread-guiding groove (7) on one side running along the stem (2) and connecting the eyes (4 and 6 in FIGS. 1, and 4 and 15 in FIG. 2). The needle also has a transitional segment (5 in FIG. 1, and 14 in FIG. 2) between the lower end of the shank (1) and the upper end of the stem (2). The stem is offset with respect to the shank (1) but runs parallel thereto; the upper eye (6 in FIG. 1, and 15 in FIG. 2) is in the transitional segment (5 in FIG. 1 and 14 in FIG. 2) and is aligned with the thread-guiding groove (7).

    摘要翻译： 公开了一种簇绒针。 针具有柄（1）和杆（2）。 针在杆（2）中具有靠近尖端（3）和上眼睛（图1中的6，图2中的15）的下眼（4）和导丝槽 7）沿着杆（2）一侧延伸并连接眼睛（图1中的4和6以及图2中的4和15）。 该针还在柄（1）的下端和杆（2）的上端之间具有过渡段（图1中为5，在图2中为14）。 杆相对于柄（1）偏移但与其平行延伸; 上眼睛（图1中的6和图2中的15）处于过渡段（图1中的5和图2中的14），并且与导纱槽（7）对准。

    Ionizable isotopic labeling reagents for relative quantification by mass spectrometry
    8.
    发明申请
    Ionizable isotopic labeling reagents for relative quantification by mass spectrometry 有权
    用于质谱相对定量的可离子化同位素标记试剂

    公开(公告)号：US20080050833A1

    公开(公告)日：2008-02-28

    申请号：US11726307

    申请日：2007-03-21

    申请人： Lloyd Smith ,  Michael Shortreed ,  Brian Frey ,  Margaret Phillips ,  Joshua Coon ,  Shane Lamos ,  Casey Krusemark ,  Peter Belshaw ,  Madhusudan Patel ,  Neil Kelleher

    发明人： Lloyd Smith ,  Michael Shortreed ,  Brian Frey ,  Margaret Phillips ,  Joshua Coon ,  Shane Lamos ,  Casey Krusemark ,  Peter Belshaw ,  Madhusudan Patel ,  Neil Kelleher

    IPC分类号： G01N33/00

    CPC分类号： C07B59/001 ,  C07B59/00 ,  C07B59/008 ,  G01N30/7233 ,  G01N2458/15 ,  Y10T436/163333 ,  Y10T436/17

    摘要： Relative quantification of metabolites by Electrospray Ionization Mass Spectrometry (ESI-MS) requiring a mechanism for simultaneous analysis of multiple analytes in two or more samples. Labeling reagents that are reactive to particular compound classes and differ only in their isotopic kit facilitating relative quantification and providing tangible evidence for the existence of specific functional groups. Heavy and light isotopic forms of methylacetimidate were synthesized and used as labeling reagents for quantification of amine-containing molecules, such as biological samples. Heavy and light isotopic forms of formaldehyde and cholamine were also synthesized and used independently as labeling reagents for quantification of amine-containing and carboxylic acid-containing molecules, such as found in biological samples. Advantageously, the labeled end-products are positively charged under normal acidic conditions involving conventional Liquid Chromatography Mass Spectrometry (LC/MS) applications. Labeled primary and secondary amine and carboxylic acid end-products also generated higher signals concerning mass-spectra than pre-cursor molecules and improved sensitivity. Improved accuracy concerning relative quantification was achieved by mixing heavy and light labeled Arabidopsis extracts in different ratios. Labeling strategy was further employed to ascertain differences in the amounts of amine-containing metabolites for two strains of Arabidopsis seeds.

    摘要翻译： 通过电喷雾离子化质谱（ESI-MS）对代谢物进行相对定量，其需要同时分析两个或多个样品中多种分析物的机制。 标记对特定化合物类别具有反应性的试剂，仅在其同位素试剂盒中有所不同，便于相对定量，并为特定官能团的存在提供有形证据。 合成了甲基亚酰亚胺酸的重和轻同位素形式，并用作定量含胺分子（如生物样品）的标记试剂。 还合成了重和轻的同位素形式的甲醛和胆胺，并且独立地用作用于定量含胺和含羧酸的分子的标记试剂，例如在生物样品中发现的。 有利地，标记的最终产物在常规的液相色谱质谱（LC / MS）应用的正常酸性条件下带正电荷。 标记的伯胺和仲胺和羧酸终产物也产生了比前体分子更高的质谱信号，提高了灵敏度。 通过以不同比例混合重和轻标记的拟南芥提取物，提高了相对定量的准确性。 进一步使用标记策略来确定两种拟南芥种子的含胺代谢物的量的差异。