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1.发明授权公开(公告)号：US08410288B2
公开(公告)日：2013-04-02
申请号：US13252682
申请日：2011-10-04
IPC分类号： C07D209/02 , A61K31/403
CPC分类号： C07D209/52 , A61K31/403
摘要： The invention provides polymorphs of Saxagliptin hydrochloride, processes for preparing polymorphs of Saxagliptin hydrochloride, and pharmaceutical compositions of polymorphs of Saxagliptin hydrochloride.
摘要翻译： 本发明提供盐酸沙格列汀的多晶型物，盐酸沙格列汀的多晶型物的制备方法，盐酸萨格列汀的多晶型物的药物组合物。
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2.发明授权Pharmaceutically acceptable salt and polymorphic forms of flupirtine maleate 有权马来酸氟吡汀的药学上可接受的盐和多晶型物公开(公告)号：US08138349B2
公开(公告)日：2012-03-20
申请号：US12309260
申请日：2007-07-13
申请人： Aleksandar Danilovski , Maja Dev{hacek over (c)}ić , Marina Marinković , Ernest Me{hacek over (s)}trović , Tina Mundorfer , Iva Tunjić
发明人： Aleksandar Danilovski , Maja Dev{hacek over (c)}ić , Marina Marinković , Ernest Me{hacek over (s)}trović , Tina Mundorfer , Iva Tunjić
IPC分类号： C07D213/00 , A61K31/44
CPC分类号： C07D213/75
摘要： The present invention is concerned with new polymorphic forms of flupirtine maleate, processes for preparing the new polymorphic forms, pharmaceutical compositions containing them, therapeutic uses thereof and methods of treatment employing them.
摘要翻译： 本发明涉及马来酸氟吡汀的新型多晶型物，新型多晶型物的制备方法，含有它们的药物组合物，其治疗用途和使用它们的治疗方法。
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3.发明申请公开(公告)号：US20120083517A1
公开(公告)日：2012-04-05
申请号：US13252682
申请日：2011-10-04
IPC分类号： A61K31/403 , A61P3/08 , C07D209/52
CPC分类号： C07D209/52 , A61K31/403
摘要： The invention provides polymorphs of Saxagliptin hydrochloride, processes for preparing polymorphs of Saxagliptin hydrochloride, and pharmaceutical compositions of polymorphs of Saxagliptin hydrochloride.
摘要翻译： 本发明提供盐酸沙格列汀的多晶型物，盐酸沙格列汀的多晶型物的制备方法，盐酸萨格列汀的多晶型物的药物组合物。
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4.发明授权Polymorphs of eltrombopag and eltrombopag salts and processes for preparation thereof 有权埃曲波帕和埃曲波帕盐的多晶型物及其制备方法公开(公告)号：US08372822B2
公开(公告)日：2013-02-12
申请号：US13486688
申请日：2012-06-01
申请人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
发明人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
IPC分类号： C07D231/46 , A61K31/4152
CPC分类号： C07D231/46
摘要： New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia.
摘要翻译： 已经获得并表征了Eltrombopag和Eltrombopag乙醇胺盐的新多晶型物。 这些多晶型物和包含它们的药物组合物可用于例如治疗导致血小板减少症的病症。
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5.发明申请Pharmaceutically acceptable salt and polymorphic forms of flupirtine maleate 有权马来酸氟吡汀的药学上可接受的盐和多晶型物公开(公告)号：US20110184030A1
公开(公告)日：2011-07-28
申请号：US12309260
申请日：2007-07-13
申请人： Aleksandar Danilovski , Maja Devcic , Marina Marinkovic , Ernest Mestrovic , Tina Mundorfer , Iva Tunjic
发明人： Aleksandar Danilovski , Maja Devcic , Marina Marinkovic , Ernest Mestrovic , Tina Mundorfer , Iva Tunjic
IPC分类号： A61K31/44 , C07D213/75 , A61P25/04 , A61P25/16 , A61P21/02
CPC分类号： C07D213/75
摘要： The present invention is concerned with new polymorphic forms of flupirtine maleate, processes for preparing the new polymorphic forms, pharmaceutical compositions containing them, therapeutic uses thereof and methods of treatment employing them.
摘要翻译： 本发明涉及马来酸氟吡汀的新型多晶型物，新型多晶型物的制备方法，含有它们的药物组合物，其治疗用途和使用它们的治疗方法。
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6.发明授权Polymorphs of eltrombopag and eltrombopag salts and processes for preparation thereof 有权埃曲波帕和埃曲波帕盐的多晶型物及其制备方法公开(公告)号：US07956048B2
公开(公告)日：2011-06-07
申请号：US12752642
申请日：2010-04-01
申请人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
发明人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
IPC分类号： C07D231/46 , A61K31/4152 , A61K31/655
CPC分类号： C07D231/46
摘要： New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia.
摘要翻译： 已经获得并表征了Eltrombopag和Eltrombopag乙醇胺盐的新多晶型物。 这些多晶型物和包含它们的药物组合物可用于例如治疗导致血小板减少症的病症。
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7.发明授权Polymorphs of eltrombopag and eltrombopag salts and processes for preparation thereof 有权埃曲波帕和埃曲波帕盐的多晶型物及其制备方法公开(公告)号：US08217021B2
公开(公告)日：2012-07-10
申请号：US13198214
申请日：2011-08-04
申请人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
发明人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
IPC分类号： C07D231/46 , A61K31/4152
CPC分类号： C07D231/46
摘要： New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia.
摘要翻译： 已经获得并表征了Eltrombopag和Eltrombopag乙醇胺盐的新多晶型物。 这些多晶型物和包含它们的药物组合物可用于例如治疗导致血小板减少症的病症。
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公开(公告)号：US08022093B2
公开(公告)日：2011-09-20
申请号：US13089482
申请日：2011-04-19
申请人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
发明人： Edislav Leksic , Helena Ceric , Tina Mundorfer , Irena Zrinski Antonac , Zrinka Mastelic Samardzic
IPC分类号： A61K31/4152 , A61K31/655 , C07D231/46
CPC分类号： C07D231/46
摘要： New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia.
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