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公开(公告)号：US07208302B2
公开(公告)日：2007-04-24
申请号：US10508356
申请日：2003-03-19
CPC分类号： C12N9/0022 , C12P41/002
摘要： The present invention relates to a method for the deracemisation or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion, simultaneously or sequentially. The invention also provides a method for selecting a suitable enzyme, particularly a suitable amine oxidase, and for the generation of novel enzymes suitable for use in the deracemisation method.
摘要翻译： 本发明涉及通过酶处理使手性胺脱甲酰化或手性反转的方法。 该方法同时或顺序地采用立体选择性酶转化和非选择性或部分选择性化学或酶转化。 本发明还提供了选择合适的酶，特别是合适的胺氧化酶的方法，以及用于产生适用于脱粒方法的新型酶的方法。
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公开(公告)号：US08178324B2
公开(公告)日：2012-05-15
申请号：US12947164
申请日：2010-11-16
CPC分类号： C12N9/0022 , C12P41/002
摘要： The present invention relates to a method for the deracemization or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion, simultaneously or sequentially. The invention also provides a method for selecting a suitable enzyme, particularly a suitable amine oxidase, and for the generation of novel enzymes suitable for use in the deracemization method.
摘要翻译： 本发明涉及通过酶处理使手性胺脱甲酰化或手性反转的方法。 该方法同时或顺序地采用立体选择性酶转化和非选择性或部分选择性化学或酶转化。 本发明还提供了选择合适的酶，特别是合适的胺氧化酶的方法，以及用于产生适用于脱粒方法的新型酶的方法。
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公开(公告)号：US20060257978A1
公开(公告)日：2006-11-16
申请号：US10508356
申请日：2003-03-19
CPC分类号： C12N9/0022 , C12P41/002
摘要： The present invention relates to a method for the deracemisation or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion, simultaneously or sequentially. The invention also provides a method for selecting a suitable enzyme, particularly a suitable amine oxidase, and for the generation of novel enzymes suitable for use in the deracemisation method.
摘要翻译： 本发明涉及通过酶处理使手性胺脱甲酰化或手性反转的方法。 该方法同时或顺序地采用立体选择性酶转化和非选择性或部分选择性化学或酶转化。 本发明还提供了选择合适的酶，特别是合适的胺氧化酶的方法，以及用于产生适用于脱粒方法的新型酶的方法。
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公开(公告)号：US20070166811A1
公开(公告)日：2007-07-19
申请号：US11685939
申请日：2007-03-14
IPC分类号： C12N9/00
CPC分类号： C12N9/0022 , C12P41/002
摘要： Methods are described for the deracemisation or chiral inversion of chiral amines by enzymatic treatment, such as by a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion, simultaneously or sequentially. Also described are methods for selecting a suitable enzyme, particularly a suitable amine oxidase, and for the generation of novel enzymes suitable for use in the deracemisation method.
摘要翻译： 描述了通过酶处理例如通过立体选择性酶转化和非选择性或部分选择性化学或酶转化同时或顺序地使手性胺进行脱甲酰化或手性反转的方法。 还描述了选择合适的酶，特别是合适的胺氧化酶的方法，以及用于产生适用于脱溶化方法的新型酶的方法。
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