公开(公告)号：US20120028222A1

公开(公告)日：2012-02-02

申请号：US13113670

申请日：2011-05-23

申请人： Mario Abdennour ,  Philip Stashenko ,  Michele Scrime ,  Jack Gilad ,  J. Max Goodson

发明人： Mario Abdennour ,  Philip Stashenko ,  Michele Scrime ,  Jack Gilad ,  J. Max Goodson

IPC分类号： A61C5/02

CPC分类号： A61K47/32 ,  A61C5/40 ,  A61K9/0063 ,  A61K9/0092

摘要： Endodontic fibers comprising a biocompatible polymer vehicle permeable to medicaments, or combinations of medicaments are described. Such fibers can be used, for example, in a method for the local delivery and sustained release of medicaments to periodontal or intracanal treatment sites. Endodontic fibers described include modified periodontal fibers and intracanal fibers.

摘要翻译： 描述了包含可渗透药物的生物相容性聚合物载体或药物组合的根管纤维。 这样的纤维可以用于例如药物局部递送和持续释放到牙周或肛门内治疗部位的方法。 所述的根管纤维包括改良的牙周纤维和颅内纤维。

公开(公告)号：US4764377A

公开(公告)日：1988-08-16

申请号：US15521

申请日：1987-02-13

申请人： J. Max Goodson

发明人： J. Max Goodson

IPC分类号： A61C19/06 ,  A61K6/00 ,  A61K9/00 ,  A61K31/65

CPC分类号： A61K9/0063 ,  A61K6/0023 ,  A61C19/063

摘要： Therapeutic agent delivery devices and methods for using them in treatment of dental disease are disclosed. In the treatment of periodontal disease, a therapeutic agent such as tetracycline mixed in a polymeric matrix such as ethylene vinyl acetate copolymer is packed into the area to be treated and kept in place for a suitable time, during which the therapeutic agent diffuses out of the polymeric matrix, providing continuous therapy for the treatment site.

公开(公告)号：US20120009539A1

公开(公告)日：2012-01-12

申请号：US13237462

申请日：2011-09-20

申请人： J. Max Goodson ,  Nikos Soukos

发明人： J. Max Goodson ,  Nikos Soukos

IPC分类号： A61N5/06 ,  A61C17/00 ,  A61C19/06 ,  A61M37/00

CPC分类号： A61C1/088 ,  A61C19/066 ,  A61N5/0603 ,  A61N2005/0606 ,  A61N2005/0652 ,  A61N2005/0662

摘要： The present invention relates to methods, systems, kits and devices that emit light to the oral cavity. The device includes a light source; a power source in electrical communication with the light source; and a bite actuated switch in electrical communication with the power source and the light source. The device is a size or shape that fits within an oral cavity of an individual. Since the device along with the light and power source are self contained, the user have their hands-free and can perform other activities while using the device. The device, methods, systems, and kits, further include the use of an agent (e.g., antibacterial agents, tooth whitening agents, cleaning agents) that assists or enhances the efficacy of the light therapy.

摘要翻译： 本发明涉及向口腔发射光的方法，系统，试剂盒和装置。 该装置包括光源; 与光源电通信的电源; 以及与电源和光源电连通的咬动致动开关。 该装置是适合于个体口腔内的尺寸或形状。 由于该设备与光源和电源一起是独立的，所以用户在使用设备时可以进行免提，并可以执行其他操作。 该装置，方法，系统和试剂盒还包括有助于或增强光疗疗效的试剂（例如，抗细菌剂，牙齿增白剂，清洁剂）的使用。

公开(公告)号：US10463879B2

公开(公告)日：2019-11-05

申请号：US15593018

申请日：2017-05-11

申请人： The Forsyth Institute ,  Nikolaos S. Soukos ,  J. Max Goodson

发明人： Nikolaos S. Soukos ,  J. Max Goodson

IPC分类号： A61N5/06

摘要： Light-based systems and methods are provided with targeted antibacterial action for mouth care in animals such as dogs. In various embodiments, the device includes a substantially impermeable shell. The shell has an outer surface. The outer surface has at least one substantially transparent region. The device further includes at least one light-emitting diode disposed within the shell. The at least one light-emitting diode is adapted to emit light having a wavelength between about 400 nm and about 1,000 nm when powered. The at least one light-emitting diode is configured to provide an average light intensity of between about 10 and about 50 mW/cm2 across the at least one substantially transparent region of the outer surface. The device further includes a power source disposed within the shell. The device further includes a switch at least partially disposed within the shell and adapted to control current flow from the power source to the at least one light-emitting diode.

公开(公告)号：US20200316400A1

公开(公告)日：2020-10-08

申请号：US16671875

申请日：2019-11-01

申请人： J. Max Goodson ,  Photomedics Inc.

发明人： Nikolaos S. Soukos ,  J. Max Goodson

IPC分类号： A61N5/06

摘要： Light-based systems and methods are provided with targeted antibacterial action for mouth care in animals such as dogs. In various embodiments, the device includes a substantially impermeable shell. The shell has an outer surface. The outer surface has at least one substantially transparent region. The device further includes at least one light-emitting diode disposed within the shell. The at least one light-emitting diode is adapted to emit light having a wavelength between about 400 nm and about 1,000 nm when powered. The at least one light-emitting diode is configured to provide an average light intensity of between about 10 and about 50 mW/cm2 across the at least one substantially transparent region of the outer surface. The device further includes a power source disposed within the shell. The device further includes a switch at least partially disposed within the shell and adapted to control current flow from the power source to the at least one light-emitting diode.

公开(公告)号：US20170326383A1

公开(公告)日：2017-11-16

申请号：US15593018

申请日：2017-05-11

申请人： Nikolaos S. Soukos ,  J. Max Goodson ,  The Forsyth Institute

发明人： Nikolaos S. Soukos ,  J. Max Goodson

IPC分类号： A61N5/06

CPC分类号： A61N5/0624 ,  A61N5/0603 ,  A61N2005/0606 ,  A61N2005/0626 ,  A61N2005/0642 ,  A61N2005/0651 ,  A61N2005/0659 ,  A61N2005/0662 ,  A61N2005/0663

摘要： Light-based systems and methods are provided with targeted antibacterial action for mouth care in animals such as dogs. In various embodiments, the device includes a substantially impermeable shell. The shell has an outer surface. The outer surface has at least one substantially transparent region. The device further includes at least one light-emitting diode disposed within the shell. The at least one light-emitting diode is adapted to emit light having a wavelength between about 400 nm and about 1,000 nm when powered. The at least one light-emitting diode is configured to provide an average light intensity of between about 10 and about 50 mW/cm2 across the at least one substantially transparent region of the outer surface. The device further includes a power source disposed within the shell. The device further includes a switch at least partially disposed within the shell and adapted to control current flow from the power source to the at least one light-emitting diode.

公开(公告)号：US4892736A

公开(公告)日：1990-01-09

申请号：US202699

申请日：1988-06-03

申请人： J. Max Goodson

发明人： J. Max Goodson

IPC分类号： A61C19/06 ,  A61K6/00 ,  A61K9/00

CPC分类号： A61K9/0063 ,  A61K6/0023 ,  A61C19/063

摘要： Therapeutic agent delivery devices and methods for using them in treatment of dental disease are disclosed. In the treatment of periodontal disease, a therapeutic agent such as tetracycline mixed in a polymeric matrix such as ethylene vinyl acetate copolymer is packed into the area to be treated and kept in place for a suitable time, during which the therapeutic agent diffuses out of the polymeric matrix, providing continuous therapy for the treatment site.

摘要翻译： 公开了治疗剂递送装置和用于治疗牙齿疾病的方法。 在牙周病的治疗中，将混合在聚合物基质如乙烯 - 乙酸乙烯酯共聚物中的四环素等治疗剂填充到待治疗的区域中并保持在适当的时间，在此期间治疗剂从 聚合物基质，为治疗部位提供连续治疗。