公开(公告)号：US20060019930A1

公开(公告)日：2006-01-26

申请号：US10514127

申请日：2003-05-14

申请人： Mark Pepys ,  Steven Ley ,  Alexander Cobb

发明人： Mark Pepys ,  Steven Ley ,  Alexander Cobb

IPC分类号： A61K31/675 ,  C07F9/547

CPC分类号： A61K49/0004 ,  A61K47/544

摘要： An agent for use in medicine, which agent comprises a plurality of ligands covalently co-linked so as to form a complex with a plurality of C-reactive protein (CRP) molecules in the presence thereof, wherein (i) at least two of the ligands are the same or different and are capable of being bound by ligand binding sites present on the CRP molecules; or (ii) at least one of the ligands is capable of being bound by a ligand binding site present on a CRP molecule, and at least one other of the ligands is capable of being bound by a ligand binding site present on a serum amyloid P component (SAP) molecule.