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1.发明申请Method for producing carotenoids or their precursors using genetically modified organisms of the blakeslea genus, carotenoids or their precursors produced by said method and use thereof 审中-公开使用所述方法生产的布鲁氏菌属，类胡萝卜素或其前体的遗传修饰生物来生产类胡萝卜素或其前体的方法及其用途公开(公告)号：US20060234333A1
公开(公告)日：2006-10-19
申请号：US10541750
申请日：2004-01-09
CPC分类号： C12N15/80 , A23K20/179 , A23L5/00 , A23L5/44 , A23L31/00 , A23L33/105 , C12P23/00
摘要： The invention relates to a method for producing carotenoids or their precursors using genetically modified organisms of the Blakeslea genus. Said method comprises the following steps (i) transformation of at least one of the cells, (ii) optional homokaryotic conversion of the cells obtained in step (i) to produce cells, in which one or more genetic characteristics of the nuclei are all modified in an identical manner and said modification manifests itself in the cells, (iii) selection and reproduction of the genetically modified cell or cells, (iv) cultivation of the genetically modified cells, (v) preparation of the carotenoids produced by the genetically modified cells or the carotenoid precursor produced by said genetically modified cells. The invention also relates to carotenoids or their precursors produced according to said method and to the use thereof.
摘要翻译： 本发明涉及使用布鲁氏菌属的转基因生物来生产类胡萝卜素或其前体的方法。 所述方法包括以下步骤：（i）至少一个细胞的转化，（ii）步骤（i）中获得的细胞的任选的同源转化以产生其中一个或多个核的遗传特征都被修饰的细胞 以相同的方式，并且所述修饰本身在细胞中，（iii）遗传修饰的细胞或细胞的选择和繁殖，（iv）遗传修饰的细胞的培养，（v）由遗传修饰的细胞产生的类胡萝卜素的制备 或由所述遗传修饰的细胞产生的类胡萝卜素前体。 本发明还涉及根据所述方法生产的类胡萝卜素或其前体及其用途。
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2.发明申请Method for the genetic modification of organisms of the genus blakeslea, corresponding organisms and the use of the same 审中-公开方法对布鲁氏菌属的生物进行遗传修饰，相应的生物及其使用公开(公告)号：US20060099670A1
公开(公告)日：2006-05-11
申请号：US10541993
申请日：2004-01-09
CPC分类号： C12P23/00 , A23K20/179 , A23L5/00 , A23L5/44 , A23L31/00 , A23L33/105 , C07K14/37 , C12N1/14 , C12N15/80
摘要： The invention relates to a method for producing a genetically modified organism of the Blakeslea genus, which method comprises the following steps (i) transformation of at least one of the cells, (ii) optional homokaryotic conversion of the cells obtained in step (i) to produce cells, in which one or more genetic characteristics of the nuclei are all modified in an identical manner and said modification manifests itself in the cells, and (iii) selection and cultivation of the genetically modified cell or cells.
摘要翻译： 本发明涉及一种用于生产布鲁氏菌属的遗传修饰生物的方法，该方法包括以下步骤：（i）转化至少一种细胞，（ii）步骤（i）中获得的细胞的任选的同源转化， 以产生其中一个或多个核的遗传特征全部以相同方式修饰的细胞，并且所述修饰本身在细胞中显现，和（iii）遗传修饰的细胞或细胞的选择和培养。
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