专利检索 ap:("Martin Bolli" OR "David Lehmann" OR "Boris Mathys" OR "Claus Mueller" OR "Oliver Nayler" OR "Beat Steiner") AND inv:"Oliver Nayler" 第 1 页

1.

发明申请
NOVEL PYRIDINE DERIVATIVES 失效
标题翻译：新型吡啶衍生物

公开(公告)号：US20120195930A1

公开(公告)日：2012-08-02

申请号：US13438657

申请日：2012-04-03

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

IPC分类号： A61K31/4439 , A61P37/06 , A61P25/00 , A61P17/00 , A61P17/06 , A61P1/00 , A61P29/00 , C07D413/14 , A61P19/02

CPC分类号： C07D409/06 , C07D413/14

摘要： The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

摘要翻译： 本发明涉及新颖的吡啶衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫抑制剂。

2.

发明授权
Thiophene derivatives as S1P1/EDG1 receptor agonists 有权
标题翻译：噻吩衍生物作为S1P1 / EDG1受体激动剂

公开(公告)号：US08003800B2

公开(公告)日：2011-08-23

申请号：US12160520

申请日：2007-01-10

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

IPC分类号： C07D271/06

CPC分类号： C07D333/22 , C07D413/04

摘要： The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH═CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.

摘要翻译： 本发明涉及式（I）的噻吩衍生物/其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫抑制剂，其中：A表示* -CO-CH = CH-，* -CO-CH2CH2-，* -CO-CH2-NH-，其中星号表示与噻吩基团连接的键式（I）和R 1 -R 3如权利要求中所定义。

3.

发明申请
Pyridin-3-yl derivatives as immunomodulating agents 有权
标题翻译：吡啶-3-基衍生物作为免疫调节剂

公开(公告)号：US20100168005A1

公开(公告)日：2010-07-01

申请号：US12310763

申请日：2007-09-06

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner

IPC分类号： A61K31/4439 , C07D413/04 , C07D417/04 , C07D413/14 , A61P37/06 , A61P17/06 , A61P1/04 , A61P3/10 , A61P11/02 , A61P11/06 , A61P17/00 , A61P29/00 , A61K38/19

CPC分类号： C07D413/04 , C07D417/04

摘要： The invention relates to pyridin-3-yl derivatives of Formula (I) wherein R1, R2, R3, R4, R5; R6 and A are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

摘要翻译： 本发明涉及式（I）的吡啶-3-基衍生物，其中R1，R2，R3，R4，R5; R6和A如描述中所述，它们的制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

4.

发明申请
Novel Pyridine Derivatives 失效
标题翻译：新型吡啶衍生物

公开(公告)号：US20090005421A1

公开(公告)日：2009-01-01

申请号：US12161909

申请日：2007-01-23

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jorg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jorg Velker

IPC分类号： A61K31/4436 , C07D213/02 , A61K31/44 , A61K31/4439 , A61P37/02 , C07D413/02 , C07D409/02

CPC分类号： C07D409/06 , C07D413/14

摘要： The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

摘要翻译： 本发明涉及新颖的吡啶衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫抑制剂。

5.

发明授权
Thiophene derivatives as S1P1/EDGE1 receptor agonists 有权
标题翻译：噻吩衍生物作为S1P1 / EDGE1受体激动剂

公开(公告)号：US08133910B2

公开(公告)日：2012-03-13

申请号：US12310762

申请日：2007-07-10

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

IPC分类号： A61K31/4245 , A61K31/381 , C07D271/06 , C07D333/22

CPC分类号： C07D413/04 , C07D333/22

摘要： The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

摘要翻译： 本发明涉及新的噻吩衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

6.

发明申请
Pyridin-4-yl derivatives as immunomodulating agents 有权
标题翻译：吡啶-4-基衍生物作为免疫调节剂

公开(公告)号：US20100063108A1

公开(公告)日：2010-03-11

申请号：US12310801

申请日：2007-09-06

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jorg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jorg Velker

IPC分类号： A61K31/4439 , C07D413/04 , C07D417/04 , A61K31/4436 , A61P37/02

CPC分类号： C07D413/04 , C07D417/04

摘要： The invention relates to pyridine derivatives of Formula (I) wherein A, R1, R2, R3, R4, R5, and R6 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

摘要翻译： 本发明涉及式（I）的吡啶衍生物，其中A，R 1，R 2，R 3，R 4，R 5和R 6如描述中所述，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

7.

发明授权
Pyridine derivatives 失效
标题翻译：吡啶衍生物

公开(公告)号：US08697732B2

公开(公告)日：2014-04-15

申请号：US13438657

申请日：2012-04-03

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

IPC分类号： A61K31/4433 , C07D413/14

CPC分类号： C07D409/06 , C07D413/14

摘要： The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

摘要翻译： 本发明涉及新颖的吡啶衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫抑制剂。

8.

发明授权
Pyridin-4-yl derivatives as immunomodulating agents 有权
标题翻译：吡啶-4-基衍生物作为免疫调节剂

公开(公告)号：US08580824B2

公开(公告)日：2013-11-12

申请号：US12310801

申请日：2007-09-06

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

IPC分类号： A61K31/443 , C07D413/04

CPC分类号： C07D413/04 , C07D417/04

摘要： The invention relates to pyridine derivatives of Formula (I) wherein A, R1, R2, R3, R4, R5, and R6 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

摘要翻译： 本发明涉及式（I）的吡啶衍生物，其中A，R 1，R 2，R 3，R 4，R 5和R 6如描述中所述，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

9.

发明授权
Thiophene derivatives 失效

公开(公告)号：US07981924B2

公开(公告)日：2011-07-19

申请号：US12094736

申请日：2006-11-22

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jörg Velker

IPC分类号： A61K31/38 , C07D333/00

CPC分类号： C07D333/72

摘要： The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

10.

发明申请
PHENYL DERIVATIVES AND THEIR USE AS IMMUNOMODULATORS 失效
标题翻译：苯乙烯衍生物及其作为免疫调节剂的使用

公开(公告)号：US20100087495A1

公开(公告)日：2010-04-08

申请号：US12442203

申请日：2007-07-10

申请人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jorg Velker

发明人： Martin Bolli , David Lehmann , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner , Jorg Velker

IPC分类号： A61K31/4245 , C07D271/06 , A61P37/04

CPC分类号： C07D271/06 , C07D271/107

摘要： The invention relates to phenyl derivatives of formula (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

摘要翻译： 本发明涉及式（I）的苯基衍生物，其制备及其作为药物活性化合物的用途。所述化合物特别充当免疫调节剂。

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