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1.Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators 审中-公开
标题翻译: 新型苯基咪唑和苯基三唑作为γ-分泌酶调节剂公开(公告)号:US20120053165A1
公开(公告)日:2012-03-01
申请号:US13203988
申请日:2010-03-02
申请人: Martin Patrick Allen , Christopher William Am Ende , Michael Aaron Brodney , Amy Beth Dounay , Douglas Scott Johnson , Martin Youngjin Pettersson , Jacob Bradley Schwartz , Tuan Phong Tran
发明人: Martin Patrick Allen , Christopher William Am Ende , Michael Aaron Brodney , Amy Beth Dounay , Douglas Scott Johnson , Martin Youngjin Pettersson , Jacob Bradley Schwartz , Tuan Phong Tran
IPC分类号: A61K31/4178 , A61K31/4164 , C07D413/12 , A61K31/422 , A61K31/4245 , C07D249/08 , A61K31/4196 , C07D405/12 , C07D409/12 , C07D403/12 , C07D417/12 , A61K31/427 , A61K31/423 , C07D403/10 , C07D401/10 , A61K31/454 , A61K31/5377 , A61K31/437 , A61P25/00 , A61P25/18 , C07D233/61
CPC分类号: C07D413/12 , C07D233/54 , C07D401/12 , C07D403/12 , C07D417/12
摘要: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
摘要翻译: 公开了化合物的化合物和药学上可接受的盐,其中所述化合物具有如说明书中定义的式(I)的结构。 还公开了相应的药物组合物,治疗方法,合成方法和中间体。