公开(公告)号：US07582875B2

公开(公告)日：2009-09-01

申请号：US11123708

申请日：2005-05-05

申请人： Massimo Caccia ,  Leopoldo Conte ,  Mario Alemi ,  Chiara Cappellini ,  Antonello Luigi Airoldi ,  Carla Bianchi ,  Raffaele Novario ,  Wim De Boer ,  Eugene Grigoriev ,  Halina Niemiec ,  Wojciech Kucewicz ,  Francesco Cannillo ,  Gilles Clauss ,  Claude Colledani ,  Grzegorz Deptuch ,  Wojciech Dulinski ,  Piotr Grabiec ,  Jacek Marczewski ,  Krzysztof Domanski ,  Bohdan Jaroszewicz ,  Krzysztof Kucharski ,  Laura Badano ,  Omella Ferrando ,  Georg Popowski ,  Agnieszka Zalewska ,  Adam Czermak

发明人： Massimo Caccia ,  Leopoldo Conte ,  Mario Alemi ,  Chiara Cappellini ,  Antonello Luigi Airoldi ,  Carla Bianchi ,  Raffaele Novario ,  Wim De Boer ,  Eugene Grigoriev ,  Halina Niemiec ,  Wojciech Kucewicz ,  Francesco Cannillo ,  Gilles Clauss ,  Claude Colledani ,  Grzegorz Deptuch ,  Wojciech Dulinski ,  Piotr Grabiec ,  Jacek Marczewski ,  Krzysztof Domanski ,  Bohdan Jaroszewicz ,  Krzysztof Kucharski ,  Laura Badano ,  Omella Ferrando ,  Georg Popowski ,  Agnieszka Zalewska ,  Adam Czermak

IPC分类号： G01T1/02

CPC分类号： G01T1/026 ,  H01L27/1443 ,  H01L27/1446 ,  H01L27/14601 ,  H01L27/14609 ,  H01L27/14643 ,  H01L27/14658

摘要： A monolithic active pixel dosimeter, provided with at least a sensing cell, having at least a junction sensing element. The junction sensing element includes a sensing region, having a first type of conductivity, and a charge collecting region, contiguous to the sensing region and having a second type of conductivity. The sensing cell further includes an ohmic region at least partially overlapping and extending laterally outside the charge collecting region, and an annular insulating region, abutting the ohmic region, so as to form an insulating junction surrounding both the ohmic region and the charge collection region.

摘要翻译： 具有至少一个感测单元的至少具有接点感测元件的单片有源像素剂量计。 接点感测元件包括具有第一类型的导电性的感测区域和与感测区域邻接且具有第二类型导电性的电荷收集区域。 感测单元还包括至少部分地重叠并在电荷收集区域外横向延伸的欧姆区域，以及邻接欧姆区域的环形绝缘区域，以形成围绕欧姆区域和电荷收集区域的绝缘结。

公开(公告)号：US20060043313A1

公开(公告)日：2006-03-02

申请号：US11123708

申请日：2005-05-05

申请人： Massimo Caccia ,  Leopoldo Conte ,  Mario Alemi ,  Chiara Cappellini ,  Antonello Airoldi ,  Carla Bianchi ,  Raffaele Novario ,  Wim De Boer ,  Eugene Grigoriev ,  Halina Niemiec ,  Wojciech Kucewicz ,  Francesco Cannillo ,  Gilles Clauss ,  Claude Colledani ,  Grzegorz Deptuch ,  Wojciech Dulinski ,  Piotr Grabiec ,  Jacek Marczewski ,  Krzysztof Domanski ,  Bohdan Jaroszewicz ,  Krzysztof Kucharski ,  Laura Badano ,  Omella Ferrando ,  Georg Popowski ,  Agnieszka Zalewska ,  Adam Czermak

发明人： Massimo Caccia ,  Leopoldo Conte ,  Mario Alemi ,  Chiara Cappellini ,  Antonello Airoldi ,  Carla Bianchi ,  Raffaele Novario ,  Wim De Boer ,  Eugene Grigoriev ,  Halina Niemiec ,  Wojciech Kucewicz ,  Francesco Cannillo ,  Gilles Clauss ,  Claude Colledani ,  Grzegorz Deptuch ,  Wojciech Dulinski ,  Piotr Grabiec ,  Jacek Marczewski ,  Krzysztof Domanski ,  Bohdan Jaroszewicz ,  Krzysztof Kucharski ,  Laura Badano ,  Omella Ferrando ,  Georg Popowski ,  Agnieszka Zalewska ,  Adam Czermak

IPC分类号： H05B33/00

CPC分类号： G01T1/026 ,  H01L27/1443 ,  H01L27/1446 ,  H01L27/14601 ,  H01L27/14609 ,  H01L27/14643 ,  H01L27/14658

摘要： A monolithic active pixel dosimeter, provided with at least a sensing cell, having at least a junction sensing element. The junction sensing element includes a sensing region, having a first type of conductivity, and a charge collecting region, contiguous to the sensing region and having a second type of conductivity. The sensing cell further includes an ohmic region at least partially overlapping and extending laterally outside the charge collecting region, and an annular insulating region, abutting the ohmic region, so as to form an insulating junction surrounding both the ohmic region and the charge collection region.

公开(公告)号：US20120232405A1

公开(公告)日：2012-09-13

申请号：US13393364

申请日：2009-08-29

申请人： Eugene Grigoriev

发明人： Eugene Grigoriev

IPC分类号： A61B6/00

CPC分类号： G01T1/161 ,  A61B6/4258

摘要： A simple and potentially disposable compact probe of FIG. 1, which is primarily aimed to be used for radio-guided or fluorescence-guided surgery, diagnostics or biopsy, and method of using it, is invented. The novel method reduces limitations inherent to the existing technologies. It consists in shifting most of the functions (signal analysis, detector controls and user visual and audio interfaces) from the probe to an external personal computer connected with the probe via wireless link. Maximum simplification and miniaturization of the probe itself makes it potentially disposable, supplied in sterile package similar to disposable syringe. Due to use of single photon time-resolved counting photo-sensors and microelectronic circuits with sub-nanosecond timing, the probe can be used with fluorescent markers as well. New probe should enhance efficiency of medical procedures and open opportunities for more wide application of the intra-operative probing techniques in medical practice, especially in oncology. Applications other than medical are also possible.

摘要翻译： 图1的简单且潜在的一次性紧凑型探针。 1，其主要目的是用于无线电引导或荧光引导手术，诊断或活检，以及使用它的方法。 新颖的方法减少了现有技术固有的局限性。 它将大多数功能（信号分析，检测器控制和用户视觉和音频接口）从探头转移到通过无线链路与探头连接的外部个人计算机。 探头本身的最大化简化和小型化使其成为潜在的一次性，在无菌包装中提供，类似于一次性注射器。 由于使用具有亚纳秒时间的单光子时分解算光电传感器和微电子电路，探针也可与荧光标记一起使用。 新的探索应该提高医疗程序的效率，并开放更广泛地应用于医学实践中的术中探查技术的机会，特别是肿瘤学。 医疗以外的应用也是可以的。