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公开(公告)号:US20090162393A1
公开(公告)日:2009-06-25
申请号:US11906440
申请日:2007-10-01
申请人: Matt Cook , Nick Elliot , Jawahar Patil , Barbara Nowak , Michael Attard , Phil Crosbie , Richard Morrison , Giles Campbell , Bronwyn Holmes , Christopher Prideaux
发明人: Matt Cook , Nick Elliot , Jawahar Patil , Barbara Nowak , Michael Attard , Phil Crosbie , Richard Morrison , Giles Campbell , Bronwyn Holmes , Christopher Prideaux
IPC分类号: A61K39/00
CPC分类号: A61K39/002 , A61K2039/53 , A61K2039/55 , G01N33/56905
摘要: The present invention provides a vaccine composition including a nucleic acid that encodes an amoeba-derived antigen (or a peptide molecule encoded thereby), or fragments or variants thereof. The present invention also provides for the use of such vaccine compositions in eliciting an immune response and/or protective immunity in a host against amoebic infection and screening a sample for the presence of amoebae.
摘要翻译: 本发明提供一种疫苗组合物,其包含编码来自阿米巴的抗原(或由其编码的肽分子)或其片段或变体的核酸。 本发明还提供了这样的疫苗组合物在宿主中引发免疫应答和/或保护性免疫以抗阿米巴感染并筛选样品以存在变形虫素的用途。