利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.019 秒)

    SYSTEM AND METHOD FOR TRANSDERMAL DRUG DELIVERY
    1.
    发明申请
    SYSTEM AND METHOD FOR TRANSDERMAL DRUG DELIVERY 失效
    用于转管药物递送的系统和方法

    公开(公告)号：US20100028388A1

    公开(公告)日：2010-02-04

    申请号：US12334379

    申请日：2008-12-12

    申请人： Matt Gibson ,  Takashi Yoshida Kozai ,  Erin Purcell

    发明人： Matt Gibson ,  Takashi Yoshida Kozai ,  Erin Purcell

    IPC分类号： A61K9/00

    CPC分类号： A61K9/703 ,  A61M35/00 ,  A61M2037/0007

    摘要： In the preferred embodiment, the invention is a system for creating micropores in the skin for transdermal drug delivery through the micropores and includes: a chemical that dissolves or breaks down superficial layers of skin; a chemical delivery element that holds and delivers controlled volumes of the chemical to skin, creating micropores; and a base that is able to temporarily couple to skin, contains the chemical delivery elements, and may activate the chemical delivery elements to administer the chemical to skin. In the preferred embodiment, the invention is a method for delivering drugs transdermally that includes providing a carrier containing a chemical delivery element with a chemical to break down superficial layers of skin; placing the carrier into contact with skin; activating the chemical delivery element; allowing the chemical to break down superficial layers of skin and creating micropores; and providing a drug to be delivered transdermally through the micropores.

    摘要翻译： 在优选的实施方案中，本发明是一种用于在皮肤中产生透皮药物通过微孔递送的微孔的系统，包括：溶解或分解皮肤表层的化学物质; 化学传递元件，其将受控体积的化学物质保持并输送到皮肤，产生微孔; 和能够暂时与皮肤接触的基底，包含化学物质输送元件，并且可以激活化学品递送元件以将化学品施用于皮肤。 在优选的实施方案中，本发明是一种通过皮肤递送药物的方法，其包括提供含化学物质的载体的化合物以分解皮肤表层; 使载体与皮肤接触; 激活化学传递元件; 使化学物质分解皮肤的表层和产生微孔; 并提供通过微孔透皮递送的药物。

    System and method for transdermal drug delivery
    2.
    发明授权
    System and method for transdermal drug delivery 失效
    用于透皮给药的系统和方法

    公开(公告)号：US08404255B2

    公开(公告)日：2013-03-26

    申请号：US12334379

    申请日：2008-12-12

    申请人： Matt Gibson ,  Takashi Yoshida Kozai ,  Erin Purcell

    发明人： Matt Gibson ,  Takashi Yoshida Kozai ,  Erin Purcell

    IPC分类号： A61K9/00

    CPC分类号： A61K9/703 ,  A61M35/00 ,  A61M2037/0007

    摘要： In the preferred embodiment, the invention is a system for creating micropores in the skin for transdermal drug delivery through the micropores and includes: a chemical that dissolves or breaks down superficial layers of skin; a chemical delivery element that holds and delivers controlled volumes of the chemical to skin, creating micropores; and a base that is able to temporarily couple to skin, contains the chemical delivery elements, and may activate the chemical delivery elements to administer the chemical to skin. In the preferred embodiment, the invention is a method for delivering drugs transdermally that includes providing a carrier containing a chemical delivery element with a chemical to break down superficial layers of skin; placing the carrier into contact with skin; activating the chemical delivery element; allowing the chemical to break down superficial layers of skin and creating micropores; and providing a drug to be delivered transdermally through the micropores.

    摘要翻译： 在优选的实施方案中，本发明是一种用于在皮肤中产生透皮药物通过微孔递送的微孔的系统，包括：溶解或分解皮肤表层的化学物质; 化学传递元件，其将受控体积的化学物质保持并输送到皮肤，产生微孔; 和能够暂时与皮肤接触的基底，包含化学物质输送元件，并且可以激活化学品递送元件以将化学品施用于皮肤。 在优选的实施方案中，本发明是一种通过皮肤递送药物的方法，其包括提供含化学物质的载体的化合物以分解皮肤表层; 使载体与皮肤接触; 激活化学传递元件; 使化学物质分解皮肤的表层和产生微孔; 并提供通过微孔透皮递送的药物。

    Modular terrain for a toy building set
    3.
    发明授权
    Modular terrain for a toy building set 失效
    模块化的地形玩具建筑集合

    公开(公告)号：US5924905A

    公开(公告)日：1999-07-20

    申请号：US937095

    申请日：1997-09-24

    申请人： Peter Cyrus ,  Steve Proctor ,  Rich Franko ,  Chris Brady ,  David Wicklander ,  Gary Franz ,  William Burns ,  Matt Gibson ,  Rebecca Jaynes

    发明人： Peter Cyrus ,  Steve Proctor ,  Rich Franko ,  Chris Brady ,  David Wicklander ,  Gary Franz ,  William Burns ,  Matt Gibson ,  Rebecca Jaynes

    IPC分类号： G09B1/10 ,  A63H33/04 ,  A63H33/08 ,  A63H33/42 ,  G09B25/04 ,  A63H33/06 ,  G09B29/12

    CPC分类号： A63H33/42 ,  A63H33/04 ,  G09B25/04

    摘要： The modular terrain for a playing structure, such as a toy building set, includes a plurality of terrain pieces. Some of the terrain pieces have a flat exterior edge. The flat exterior edge is only matable with a flat exterior edge on another of the terrain pieces. The flat exterior edge has spaced longitudinal end points. The flat exterior edge has no change in height between the spaced longitudinal end points. The distance between the spaced longitudinal end points of the flat exterior edge is one of Y, .sqroot.2Y and 2.sqroot.2Y. Some of the terrain pieces have a hill exterior edge. The hill exterior edge is only matable with a hill exterior edge on another of the terrain pieces. The hill exterior edge has spaced longitudinal end points. The hill exterior edge has a change in height between the spaced longitudinal end points of X. The distance between the spaced longitudinal end points of the hill exterior edge is Y. Some of the terrain pieces have a slope exterior edge. The slope exterior edge is only matable with a slope exterior edge on another of the terrain pieces. The slope exterior edge has spaced longitudinal end points. The slope exterior edge has a change in height between the spaced longitudinal end points of X. The distance between the spaced longitudinal end points of the sloped exterior edge is 2Y.

    摘要翻译： 用于玩具结构的模块化地形，例如玩具建筑物组合，包括多个地形块。 一些地形件具有平坦的外部边缘。 平坦的外部边缘仅在另一个地形件上具有平坦的外部边缘。 平坦的外边缘具有间隔的纵向端点。 平坦的外边缘在间隔的纵向端点之间的高度上没有变化。 平面外边缘间隔的纵向端点之间的距离是Y，2ROOT + E，rad 2 + EE Y和2 2ROOT + E，rad 2 + EE Y之一之间的距离。一些地形具有山丘外部边缘。 山坡的外部边缘仅与另一个地形部分上的山丘外部边缘相配。 山坡外缘具有间隔的纵向端点。 山坡外缘在X的间隔的纵向端点之间具有高度变化。山坡外缘的间隔的纵向端点之间的距离为Y.一些地形块具有斜坡外边缘。 斜坡外边缘仅与另一个地形块上的边坡外边缘配合。 斜坡外缘具有间隔的纵向端点。 斜坡外缘在X的间隔的纵向端点之间具有高度变化。倾斜外边缘的间隔的纵向端点之间的距离为2Y。

    Modular base units for a toy building set
    4.
    发明授权
    Modular base units for a toy building set 失效
    用于玩具组合的模块化基座单元

    公开(公告)号：US6129605A

    公开(公告)日：2000-10-10

    申请号：US936861

    申请日：1997-09-24

    申请人： Peter Cyrus ,  Sean Cryan ,  Steve Proctor ,  Rich Franko ,  Chris Brady ,  David Wicklander ,  Gary Franz ,  William Burns ,  Matt Gibson ,  Rebecca Jaynes

    发明人： Peter Cyrus ,  Sean Cryan ,  Steve Proctor ,  Rich Franko ,  Chris Brady ,  David Wicklander ,  Gary Franz ,  William Burns ,  Matt Gibson ,  Rebecca Jaynes

    IPC分类号： A63H33/04 ,  A63H33/08

    CPC分类号： A63H33/04

    摘要： The modular base for a playing structure, such as a toy building set, includes a first planar member, or tile base, having attachment fittings on its bottom for removable attachment to a substructure, such as a lattice. The top of the first planar member has attachment fittings thereon. Preferably, each of the attachment fittings on the top of the first planar member are aligned with one of the attachment fittings on the bottom to form a common opening through the first planar member. The modular base also includes a second planar member, or tile, having attachment fittings on its bottom. The attachment fittings are preferably protrusions that are most preferably clover leaf in shape and have an interference fit with the attachment fittings on the top of the first planar member that are most preferably square openings.

    摘要翻译： 用于玩具结构的模块化基座，例如玩具建筑物组件，包括第一平面构件或瓦片底座，在其底部具有附接配件，用于可拆卸地附接到诸如格子之类的底层结构。 第一平面构件的顶部在其上具有附接配件。 优选地，第一平面构件的顶部上的每个附接配件与底部上的附接配件中的一个对准，以形成通过第一平面构件的公共开口。 模块化底座还包括在其底部具有附接配件的第二平面构件或瓦片。 附接配件优选地是最优选的是三叶草叶片的突起，并且与第一平面构件的顶部上的最佳方形开口的附接配件具有过盈配合。

    Modular buildings for a toy building set
    5.
    发明授权
    Modular buildings for a toy building set 失效
    用于玩具建筑的模块化建筑物

    公开(公告)号：US5993283A

    公开(公告)日：1999-11-30

    申请号：US940618

    申请日：1997-09-30

    申请人： Peter Cyrus ,  Sean Cryan ,  Steve Proctor ,  Rich Franko ,  Chris Brady ,  David Wicklander ,  Gary Franz ,  Matt Gibson

    发明人： Peter Cyrus ,  Sean Cryan ,  Steve Proctor ,  Rich Franko ,  Chris Brady ,  David Wicklander ,  Gary Franz ,  Matt Gibson

    IPC分类号： A63H33/04 ,  A63H33/08 ,  A63H33/10 ,  A63H33/42 ,  G09B25/04 ,  E04B2/00

    CPC分类号： A63H33/42 ,  A63H33/04 ,  A63H33/044 ,  A63H33/086 ,  A63H33/10 ,  G09B25/04

    摘要： A modular building for a toy building set includes a planar member, or foundation, having raised ribs on its top and a wall member having a wall portion and a base portion. The wall portion of the wall member is substantially orthogonal to the base portion of the wall member. The base portion of the wall member has a cleft therein sized to receive one of the ribs of the foundation to removably attach the wall member to the foundations. A substantially planar coupler connects at least two or more of the foundation. The coupler has at least two clefts therein. The clefts are sized to receive the ribs on each of the two foundations for removable attachment of the foundation to the coupler.

    摘要翻译： 用于玩具建筑物的模块化建筑物包括平面构件或基座，其顶部具有凸肋，壁构件具有壁部和基部。 壁构件的壁部基本上垂直于壁构件的基部。 壁构件的基部具有其中的间隙，其尺寸设置成容纳基座的一个肋，以将壁构件可移除地附接到基座。 基本上平面的耦合器连接至少两个或更多个基座。 耦合器中至少有两个裂缝。 缝隙的尺寸设计成可容纳两个基座中的每一个上的肋条，用于将基座可移除地连接到联接器上。