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公开(公告)号：US20090299640A1
公开(公告)日：2009-12-03
申请号：US12094898
申请日：2006-11-17
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158
摘要： Disclosed are compositions and methods related intrinsic gene sets and methods and compositions related to detecting and classifying cancer.
摘要翻译： 公开了与检测和分类癌症相关的内在基因组和方法和组合物的组合物和方法。
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公开(公告)号：US20130345161A1
公开(公告)日：2013-12-26
申请号：US13690891
申请日：2012-11-30
申请人： Charles M. Perou , Philip S. Bernard , Torsten O. Nielsen , Matthew J. Ellis , Joel S. Parker , Miguel Martin , Eva Carrasco , Rosalia Caballero
发明人： Charles M. Perou , Philip S. Bernard , Torsten O. Nielsen , Matthew J. Ellis , Joel S. Parker , Miguel Martin , Eva Carrasco , Rosalia Caballero
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/158
摘要： The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including a taxane or a taxane derivative. The application also describes methods for treating subjects with breast cancer by screening them for the likelihood of the effectiveness of treating the cancer with a therapy including a taxane or a taxane derivative and administering the therapy in subjects when it is found that a taxane or a taxane derivative is likely to be effective.
摘要翻译： 本申请描述了筛选乳腺癌患者的方法，以确定乳腺癌是否对包括紫杉烷或紫杉烷衍生物在内的乳腺癌治疗有反应。 本申请还描述了通过对治疗患有乳腺癌的受试者的方法进行筛选，以便通过包括紫杉烷或紫杉烷衍生物在内的治疗癌症的有效性的可能性进行筛选，并且当发现紫杉烷或紫杉烷 衍生产品很可能有效。
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公开(公告)号：US09066963B2
公开(公告)日：2015-06-30
申请号：US13421367
申请日：2012-03-15
IPC分类号： A61K31/704 , A61K31/7042 , A61K45/06 , A61K31/513 , A61K31/675 , C12Q1/68
CPC分类号： C12Q1/6886 , A61K31/513 , A61K31/675 , A61K31/704 , A61K31/7042 , A61K45/06 , C12Q2600/106 , C12Q2600/158 , G01N33/57415 , G01N2333/82 , G01N2800/52 , A61K2300/00
摘要： The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including an anthracycline. The application also describes methods for treating subjects with breast cancer by screening them for the likelihood of the effectiveness of treating the cancer with a therapy including anthracycline and administering the therapy in subjects when it is found that anthracycline is likely to be effective.
摘要翻译： 本申请描述了筛选乳腺癌患者的方法，以确定乳腺癌是否对包括蒽环类药物在内的乳腺癌治疗有反应。 本申请还描述了通过筛选它们来治疗患有乳腺癌的受试者的方法，其中包括蒽环类药物治疗癌症的可能性，并且当发现蒽环类药物有效时，在受试者中进行治疗。
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公开(公告)号：US09181588B2
公开(公告)日：2015-11-10
申请号：US13690891
申请日：2012-11-30
申请人： Charles M. Perou , Philip S. Bernard , Torsten O. Nielsen , Matthew J. Ellis , Joel S. Parker , Miguel Martin , Eva Carrasco , Rosalia Caballero
发明人： Charles M. Perou , Philip S. Bernard , Torsten O. Nielsen , Matthew J. Ellis , Joel S. Parker , Miguel Martin , Eva Carrasco , Rosalia Caballero
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/158
摘要： The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including a taxane or a taxane derivative. The application also describes methods for treating subjects with breast cancer by screening them for the likelihood of the effectiveness of treating the cancer with a therapy including a taxane or a taxane derivative and administering the therapy in subjects when it is found that a taxane or a taxane derivative is likely to be effective.
摘要翻译： 本申请描述了筛选乳腺癌患者的方法，以确定乳腺癌是否对包括紫杉烷或紫杉烷衍生物在内的乳腺癌治疗有反应。 本申请还描述了通过对治疗患有乳腺癌的受试者的方法进行筛选，以便通过包括紫杉烷或紫杉烷衍生物在内的治疗癌症的有效性的可能性进行筛选，并且当发现紫杉烷或紫杉烷 衍生产品很可能有效。
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公开(公告)号：US20130004482A1
公开(公告)日：2013-01-03
申请号：US13421367
申请日：2012-03-15
IPC分类号： A61K31/704 , A61K31/675 , A61K31/513 , A61K31/519 , A61K39/395 , A61K33/24 , A61K31/7068 , A61K31/565 , A61K38/02 , A61P35/00 , G01N33/574 , C12Q1/68 , G01N21/64 , C40B30/04 , C40B40/06 , A61K31/136
CPC分类号： C12Q1/6886 , A61K31/513 , A61K31/675 , A61K31/704 , A61K31/7042 , A61K45/06 , C12Q2600/106 , C12Q2600/158 , G01N33/57415 , G01N2333/82 , G01N2800/52 , A61K2300/00
摘要： The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including an anthracycline. The application also describes methods for treating subjects with breast cancer by screening them for the likelihood of the effectiveness of treating the cancer with a therapy including anthracycline and administering the therapy in subjects when it is found that anthracycline is likely to be effective.
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