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1.发明授权Systems and methods for making and using electrical stimulation systems with improved RF compatibility 有权制造和使用具有改进射频兼容性的电刺激系统的系统和方法公开(公告)号：US08868207B2
公开(公告)日：2014-10-21
申请号：US13357910
申请日：2012-01-25
摘要： An implantable electrical stimulation lead includes a plurality of conductors that extend along a lead body and that electrically couple electrodes to terminals. A first tissue coupler is electrically coupled to a first conductor of the plurality of conductors. The first tissue coupler includes a conductive first inner member, a non-conductive member disposed adjacent to at least a portion of the first inner member, and a conductive outer member disposed adjacent to at least a portion of the non-conductive member such that at least a portion of the non-conductive member is sandwiched between the first inner member and the outer member. The first inner member is electrically coupled to the first conductor. The outer member is disposed along a portion of an outer surface of the lead body such that the conductive outer member is exposed to patient tissue when the lead is implanted in a patient.
摘要翻译： 可植入电刺激引线包括沿引线主体延伸并且将电极电连接到端子的多个导体。 第一组织耦合器电耦合到多个导体的第一导体。 第一组织联接器包括导电的第一内部构件，邻近第一内部构件的至少一部分设置的非导电构件以及邻近非导电构件的至少一部分设置的导电外部构件，使得在 非导电构件的至少一部分夹在第一内构件和外构件之间。 第一内部构件电耦合到第一导体。 外部构件沿着引线主体的外表面的一部分设置，使得当将引线植入患者时，导电外部构件暴露于患者组织。
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2.发明授权Systems and methods for making and using leads for electrical stimulation systems with improved RF compatibility 有权用于制造和使用具有改进的RF兼容性的电刺激系统的引线的系统和方法公开(公告)号：US08909352B2
公开(公告)日：2014-12-09
申请号：US13325827
申请日：2011-12-14
摘要： An implantable electrical stimulation lead includes a plurality of conductors disposed in a lead body, the plurality of conductors each electrically coupling at least one electrode to at least one terminal. The plurality of conductors includes a first conductor and a second conductor. The first conductor includes a plurality of alternating first and second coiled regions. The first coiled regions have tighter pitches than the second coiled regions. The second conductor includes a plurality of alternating third and fourth coiled regions. The third coiled regions have tighter pitches than the fourth coiled regions. The plurality of conductors are arranged into repeating adjacent winding geometries disposed along a longitudinal length of the lead body. The repeating adjacent winding geometries each include one of the plurality of first coiled regions and one of the plurality of third coiled regions axially disposed adjacent to one another.
摘要翻译： 可植入电刺激引线包括设置在引线主体中的多个导体，所述多个导体各自将至少一个电极电耦合到至少一个端子。 多个导体包括第一导体和第二导体。 第一导体包括多个交替的第一和第二线圈区域。 第一线圈区域具有比第二线圈区域更紧的间距。 第二导体包括多个交替的第三和第四线圈区域。 第三线圈区域具有比第四线圈区域更紧的间距。 多个导体被布置成沿着引线主体的纵向长度布置的重复的相邻绕组几何形状。 重复的相邻绕组几何形状各自包括多个第一卷绕区域中的一个，并且多个第三卷绕区域中的一个轴向地彼此相邻布置。
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3.发明授权Insulator layers for leads of implantable electric stimulation systems and methods of making and using 有权用于可植入电刺激系统的引线的绝缘层和制造和使用方法公开(公告)号：US08478423B2
公开(公告)日：2013-07-02
申请号：US12419738
申请日：2009-04-07
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/086 , Y10T29/49117
摘要： An implantable lead includes a plurality of conductors disposed in an elongated member. At least one of the conductors includes at least one unit that includes a first conductor segment extending along the elongated member from a beginning point to a first position, a second conductor segment extending along the elongated member from the first position to a second position, and a third conductor segment extending from the second position to an endpoint. An inner insulator layer is disposed along at least a portion of the elongated member and is formed of a material that is flowable to fill in at least some open spaces between portions of at least one of the units. An outer insulator layer is disposed over at least a portion of the inner insulator layer. The outer insulator layer has at least one physical characteristic different from the inner insulator layer.
摘要翻译： 可植入引线包括设置在细长构件中的多个导体。 至少一个导体包括至少一个单元，其包括沿着细长构件从起始点延伸到第一位置的第一导体段，沿着细长构件从第一位置延伸到第二位置的第二导体段，以及 从第二位置延伸到端点的第三导体段。 内部绝缘体层沿着细长构件的至少一部分设置，并且由可流动的材料形成，以填充至少一个单元的部分之间的至少一些开放空间。 外绝缘体层设置在内绝缘体层的至少一部分上。 外部绝缘体层具有与内部绝缘体层不同的至少一种物理特性。
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4.发明申请SYSTEMS AND METHODS FOR DISPOSING ONE OR MORE LAYERS OF MATERIAL BETWEEN LEAD CONDUCTOR SEGMENTS OF ELECTRICAL STIMULATION SYSTEMS 有权用于处理电刺激系统导线导体部分之间的一层或多层材料的系统和方法公开(公告)号：US20110046706A1
公开(公告)日：2011-02-24
申请号：US12544013
申请日：2009-08-19
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/086 , Y10T29/49174
摘要： An implantable lead includes a lead body having a plurality of electrodes disposed on a distal end, a plurality of terminals disposed on a proximal end, and a plurality of conductors, each conductor electrically coupling at least one of the electrodes to at least one of the terminals. At least one of the conductors includes at least one unit having a multi-layer region of overlapping conductor segments. The unit including a first conductor segment extending from a beginning point to a first position, a second conductor segment extending from the first position to a second position, and a third conductor segment extending from the second position to an endpoint. The first position is between the second position and the endpoint. The second position is between the beginning point and the first position. An interlayer material is disposed between the overlapping conductor segments of the at least one multi-layer region.
摘要翻译： 可植入引线包括引线本体，其具有设置在远端的多个电极，设置在近端的多个端子和多个导体，每个导体将至少一个电极电耦合到至少一个电极 终端。 至少一个导体包括至少一个具有重叠导体段的多层区域的单元。 所述单元包括从起始点延伸到第一位置的第一导体段，从第一位置延伸到第二位置的第二导体段和从第二位置延伸到端点的第三导体段。 第一个位置在第二个位置和端点之间。 第二个位置在起始点和第一个位置之间。 中间层材料设置在至少一个多层区域的重叠导体段之间。
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5.发明授权Systems and methods for electrically disconnecting components of implantable electrical systems 有权用于电气断开可植入电气系统部件的系统和方法公开(公告)号：US08548582B2
公开(公告)日：2013-10-01
申请号：US13531098
申请日：2012-06-22
IPC分类号： A61N1/36
CPC分类号： A61N1/3718 , A61N1/05 , A61N1/3752
摘要： An implantable electrical stimulation system includes a control module electrically coupleable to a lead. The control module includes a housing, an electronic subassembly disposed in the housing, and a connector assembly for receiving the lead. The connector assembly includes a port for receiving a proximal end of the lead. Connector contacts are disposed in the connector assembly housing and electrically couple to the electronic subassembly. The connector contacts align with terminals disposed on the lead to form an electrical connection between the connector contacts and the terminals when the proximal end of the lead is disposed in the port of the connector assembly. A disconnecting feature includes a switch for electrically disabling, or at least significantly reducing, the electrical connection between the connector contacts and the electronic subassembly when the switch is opened.
摘要翻译： 可植入电刺激系统包括电耦合到引线的控制模块。 控制模块包括壳体，设置在壳体中的电子组件和用于接收引线的连接器组件。 连接器组件包括用于接收引线的近端的端口。 连接器触点设置在连接器组件壳体中并电耦合到电子组件。 当引线的近端设置在连接器组件的端口中时，连接器触头与设置在引线上的端子对准，以在连接器触头和端子之间形成电连接。 断开功能包括用于在开关断开时电连接或至少显着地减小连接器触头和电子组件之间的电连接的开关。
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6.发明授权Systems and methods for altering one or more RF-response properties of electrical stimulation systems 有权用于改变电刺激系统的一个或多个RF响应特性的系统和方法公开(公告)号：US08380324B2
公开(公告)日：2013-02-19
申请号：US12544903
申请日：2009-08-20
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/056 , A61N1/086 , H01R2201/12 , Y10T29/49117
摘要： An implantable lead includes a lead body and at least one safety element. The lead body has a distal end and a proximal end. The lead body defines at least one lumen extending along at least a portion of the lead body. The lead body includes a plurality of electrodes disposed on the distal end of the lead body, a plurality of terminals disposed on the proximal end of the lead body, and a plurality of conductors disposed in the lead body, each conductor electrically coupling at least one of the electrodes to at least one of the terminals. The at least one safety element is disposed along at least a portion of the lead body and is configured and arranged to reduce damage to patient tissue adjacent to the plurality of electrodes due to heating, induced electrical signals, or both when the lead is exposed to radio frequency irradiation.
摘要翻译： 可植入引线包括引线体和至少一个安全元件。 引线体具有远端和近端。 引线体限定沿着引线主体的至少一部分延伸的至少一个内腔。 引线体包括设置在引线主体的远端上的多个电极，设置在引线主体的近端上的多个端子和布置在引线主体中的多个导体，每个导体电耦合至少一个 的至少一个端子。 所述至少一个安全元件沿着所述引线主体的至少一部分设置，并且被配置和布置成在引线暴露于所述引线体时由于加热，感应的电信号或两者而减小对与所述多个电极相邻的患者组织的损伤 射频照射
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7.发明申请SYSTEMS AND METHODS FOR MAKING AND USING ELECTRICAL STIMULATION SYSTEMS WITH IMPROVED RF COMPATIBILITY 有权制造和使用电刺激系统与提高射频兼容性的系统和方法公开(公告)号：US20120191167A1
公开(公告)日：2012-07-26
申请号：US13357910
申请日：2012-01-25
IPC分类号： A61N1/05
摘要： An implantable electrical stimulation lead includes a plurality of conductors that extend along a lead body and that electrically couple electrodes to terminals. A first tissue coupler is electrically coupled to a first conductor of the plurality of conductors. The first tissue coupler includes a conductive first inner member, a non-conductive member disposed adjacent to at least a portion of the first inner member, and a conductive outer member disposed adjacent to at least a portion of the non-conductive member such that at least a portion of the non-conductive member is sandwiched between the first inner member and the outer member. The first inner member is electrically coupled to the first conductor. The outer member is disposed along a portion of an outer surface of the lead body such that the conductive outer member is exposed to patient tissue when the lead is implanted in a patient.
摘要翻译： 可植入电刺激引线包括沿引线主体延伸并且将电极电连接到端子的多个导体。 第一组织耦合器电耦合到多个导体的第一导体。 第一组织联接器包括导电的第一内部构件，邻近第一内部构件的至少一部分设置的非导电构件以及邻近非导电构件的至少一部分设置的导电外部构件，使得在 非导电构件的至少一部分夹在第一内构件和外构件之间。 第一内部构件电耦合到第一导体。 外部构件沿着引线主体的外表面的一部分设置，使得当将引线植入患者时，导电外部构件暴露于患者组织。
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8.发明申请SYSTEMS AND METHODS FOR MAKING AND USING LEADS FOR ELECTRICAL STIMULATION SYSTEMS WITH IMPROVED RF COMPATIBILITY 有权制造和使用电刺激系统的引线与提高RF兼容性的系统和方法公开(公告)号：US20120158072A1
公开(公告)日：2012-06-21
申请号：US13325827
申请日：2011-12-14
摘要： An implantable electrical stimulation lead includes a plurality of conductors disposed in a lead body, the plurality of conductors each electrically coupling at least one electrode to at least one terminal. The plurality of conductors includes a first conductor and a second conductor. The first conductor includes a plurality of alternating first and second coiled regions. The first coiled regions have tighter pitches than the second coiled regions. The second conductor includes a plurality of alternating third and fourth coiled regions. The third coiled regions have tighter pitches than the fourth coiled regions. The plurality of conductors are arranged into repeating adjacent winding geometries disposed along a longitudinal length of the lead body. The repeating adjacent winding geometries each include one of the plurality of first coiled regions and one of the plurality of third coiled regions axially disposed adjacent to one another.
摘要翻译： 可植入电刺激引线包括设置在引线主体中的多个导体，所述多个导体各自将至少一个电极电耦合到至少一个端子。 多个导体包括第一导体和第二导体。 第一导体包括多个交替的第一和第二线圈区域。 第一线圈区域具有比第二线圈区域更紧的间距。 第二导体包括多个交替的第三和第四线圈区域。 第三线圈区域具有比第四线圈区域更紧的间距。 多个导体被布置成沿着引线主体的纵向长度布置的重复的相邻绕组几何形状。 重复的相邻绕组几何形状各自包括多个第一卷绕区域中的一个，并且多个第三卷绕区域中的一个轴向地彼此相邻布置。
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9.发明授权Systems and methods for disposing one or more layers of material between lead conductor segments of electrical stimulation systems 有权在电刺激系统的引线导体段之间布置一层或多层材料的系统和方法公开(公告)号：US08406897B2
公开(公告)日：2013-03-26
申请号：US12544013
申请日：2009-08-19
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/086 , Y10T29/49174
摘要： An implantable lead includes a lead body having a plurality of electrodes disposed on a distal end, a plurality of terminals disposed on a proximal end, and a plurality of conductors, each conductor electrically coupling at least one of the electrodes to at least one of the terminals. At least one of the conductors includes at least one unit having a multi-layer region of overlapping conductor segments. The unit including a first conductor segment extending from a beginning point to a first position, a second conductor segment extending from the first position to a second position, and a third conductor segment extending from the second position to an endpoint. The first position is between the second position and the endpoint. The second position is between the beginning point and the first position. An interlayer material is disposed between the overlapping conductor segments of the at least one multi-layer region.
摘要翻译： 可植入引线包括引线本体，其具有设置在远端的多个电极，设置在近端的多个端子和多个导体，每个导体将至少一个电极电耦合到至少一个电极 终端。 至少一个导体包括至少一个具有重叠导体段的多层区域的单元。 所述单元包括从起始点延伸到第一位置的第一导体段，从第一位置延伸到第二位置的第二导体段和从第二位置延伸到端点的第三导体段。 第一个位置在第二个位置和端点之间。 第二个位置在起始点和第一个位置之间。 中间层材料设置在至少一个多层区域的重叠导体段之间。
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10.发明申请SYSTEMS AND METHODS FOR ELECTRICALLY DISCONNECTING COMPONENTS OF IMPLANTABLE ELECTRICAL SYSTEMS 有权用于电气断开可插拔电气系统组件的系统和方法公开(公告)号：US20130006316A1
公开(公告)日：2013-01-03
申请号：US13531098
申请日：2012-06-22
CPC分类号： A61N1/3718 , A61N1/05 , A61N1/3752
摘要： An implantable electrical stimulation system includes a control module electrically coupleable to a lead. The control module includes a housing, an electronic subassembly disposed in the housing, and a connector assembly for receiving the lead. The connector assembly includes a port for receiving a proximal end of the lead. Connector contacts are disposed in the connector assembly housing and electrically couple to the electronic subassembly. The connector contacts align with terminals disposed on the lead to form an electrical connection between the connector contacts and the terminals when the proximal end of the lead is disposed in the port of the connector assembly. A disconnecting feature includes a switch for electrically disabling, or at least significantly reducing, the electrical connection between the connector contacts and the electronic subassembly when the switch is opened.
摘要翻译： 可植入电刺激系统包括电耦合到引线的控制模块。 控制模块包括壳体，设置在壳体中的电子组件和用于接收引线的连接器组件。 连接器组件包括用于接收引线的近端的端口。 连接器触点设置在连接器组件壳体中并电耦合到电子组件。 当引线的近端设置在连接器组件的端口中时，连接器触头与设置在引线上的端子对准，以在连接器触头和端子之间形成电连接。 断开功能包括用于在开关断开时电连接或至少显着地减小连接器触头和电子组件之间的电连接的开关。
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