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公开(公告)号：US6085743A
公开(公告)日：2000-07-11
申请号：US866138
申请日：1997-05-30
CPC分类号： G01R33/28 , A61M16/12 , A61M2202/0291 , G01R33/5601 , Y10S128/27
摘要： A system, and corresponding method, that interfaces with a gas polarization system to deliver a polarized noble gas to a subject for inhalation. Large volumes of polarized noble gas are obtained by repeated production/freezing cycles of a spin-exchange system. A storage cylinder is provided for storing a polarized noble gas. A gas delivery line is coupled to the storage cylinder and selectively delivers the polarized noble gas to the storage cylinder, and from the storage cylinder to the subject. A vacuum means is in communication with the gas delivery line for evacuating the storage cylinder in the gas delivery line prior to the noble gas being delivered thereto. A plurality of non-metallic gas delivery valves, located between the gas delivery line and the vacuum means, selectively control communication between the vacuum means and the polarized noble gas to minimize depolarization of the polarized noble gas during delivery of the noble gas to the subject on a breath-by-breath basis, or at a constant delivery rate. Control of remotely activated pneumatic valves allows complete automation of the polarization/accumulation/storage/delivery cycle for use in a low maintenance commercial device suitable for clinical and research applications. The polarization stage can be optimized for a particular noble gas species and particular application by the specific programming of the control electronics or computer.
摘要翻译： 与气体极化系统接合以将偏振的惰性气体输送到受试者进行吸入的系统和相应的方法。 通过自旋交换系统的反复生产/冷冻循环获得大量的极化惰性气体。 提供存储圆柱体用于存储极化的惰性气体。 气体输送管线联接到存储筒并且选择性地将偏振的惰性气体输送到存储缸，并且从存储缸向对象输送。 在惰性气体输送到真空装置之前，真空装置与气体输送管线连通，用于排出气体输送管线中的储存筒。 位于气体输送管线和真空装置之间的多个非金属气体输送阀选择性地控制真空装置和极化惰性气体之间的连通，以使惰性气体向主体输送期间极化惰性气体的去极化最小化 以呼吸为基础，或以恒定的传送速率。 远程激活的气动阀的控制允许完全自动化用于适用于临床和研究应用的低维护商业设备的偏振/积聚/存储/传送周期。 可以通过控制电子设备或计算机的特定编程，为特定惰性气体种类和特定应用优化极化阶段。
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公开(公告)号：US20170003363A1
公开(公告)日：2017-01-05
申请号：US15125846
申请日：2015-03-13
CPC分类号： G01R33/445 , G01N24/10 , G01R33/288 , G01R33/34053 , G01R33/381 , G01R33/56 , G01R33/5601 , G01R33/5611 , G01R33/5614 , G01R33/60 , G01R33/62
摘要： A system and method for performing a medical imaging process includes arranging a subject to be imaged in a magnetic resonance imaging (MRI) system and performing, using the MRI system, a magnetic resonance (MR) imaging pulse sequence. While performing the MR pulse sequence, electron paramagnetic resonance (EPR) pulses are performed at least during the application of the phase encoding gradients or only during the MR pulse sequence. Data is acquired that corresponds to signals from the subject excited by the MR pulse sequence and the EPR pulses. At least one image of the subject is reconstructed from the data.
摘要翻译： 用于执行医学成像过程的系统和方法包括将要成像的对象布置在磁共振成像（MRI）系统中，并且使用MRI系统执行磁共振（MR）成像脉冲序列。 在执行MR脉冲序列时，至少在施加相位编码梯度期间或仅在MR脉冲序列期间执行电子顺磁共振（EPR）脉冲。 获取对应于由MR脉冲序列和EPR脉冲激发的受试者的信号的数据。 从数据重建主体的至少一个图像。
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