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公开(公告)号:US4459286A
公开(公告)日:1984-07-10
申请号:US462594
申请日:1983-01-31
IPC分类号: A61K39/095 , A61K39/102 , A61K39/40 , C07G7/00
CPC分类号: A61K39/095 , A61K39/102 , A61K2039/6068 , A61K2039/627 , Y10S530/806 , Y10S530/807 , Y10S530/825
摘要: Haemophilus influenzae type B polysaccharide is coupled through a spacer to a serotype outer membrane protein from Neisseria meningitidis. This conjugate has enhanced antigenicity and immunogenicity relative to the unconjugated polysaccharide.
摘要翻译: 流感嗜血杆菌B型多糖通过间隔物与来自脑膜炎奈瑟球菌的血清型外膜蛋白偶联。 该缀合物相对于非共轭多糖具有增强的抗原性和免疫原性。