公开(公告)号：US10731163B2

公开(公告)日：2020-08-04

申请号：US15508424

申请日：2015-09-02

申请人： Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft

发明人： Markus Landthaler ,  Yasuhiro Murakawa

IPC分类号： C12N15/113 ,  C12Q1/6897

摘要： An antisense oligonucleotide comprising a sequence targeted to the 3′ untranslated region (3′ UTR) of the TNFAIP3 (A20) transcript and its use as a medicament, for example in the treatment of cancer or an autoimmune disease.

公开(公告)号：US20170298359A1

公开(公告)日：2017-10-19

申请号：US15508424

申请日：2015-09-02

申请人： Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft

发明人： Markus Landthaler ,  Yasuhiro Murakawa

IPC分类号： C12N15/113 ,  C12Q1/68

摘要： An antisense oligonucleotide comprising a sequence targeted to the 3′ untranslated region (3′ UTR) of the TNFAIP3 (A20) transcript and its use as a medicament, for example in the treatment of cancer or an autoimmune disease.