专利检索 ap:("Medarex, Inc.") AND inv:"Frank J. Carr" 第 1 页

1.

发明申请
Humanized antibodies to Fc receptors for immunoglobulin G on human mononuclear phagocytes 审中-公开

公开(公告)号：US20030144483A1

公开(公告)日：2003-07-31

申请号：US10229335

申请日：2002-08-26

申请人： Medarex, Inc.

发明人： Philip R. Tempest , William J. Harris , Frank J. Carr

IPC分类号： C07K016/30

CPC分类号： C07K16/283 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/565 , C07K2317/732

摘要： Humanized antibodies are described which are specific to an Fc receptor (FcR). The humanized antibodies have at least a portion of a complementarity determining region (CDR) derived from a non-human antibody, e.g., murine, with the remaining portions being human in origin. The humanized antibodies can be used therapeutically as is or formulated as bifunctional molecules or immunotoxins.