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公开(公告)号：US20150283194A1
公开(公告)日：2015-10-08
申请号：US14436332
申请日：2013-12-18
Inventor： Jui-Ching Chen , Che-Yi Lin , Yu-Hsiang Huang , Ming-Yu Chao , Chih-Sheng Hung
IPC: A61K36/28 , A61K31/485
CPC classification number: A61K36/28 , A61K31/485 , A61K2236/00
Abstract: Disclosed herein is the use of an extract from an Aster species for the preparation of a medicament for the treatment of pain. The extract is extracted from fresh and/or dried roots and rhizomes of a Tatarian aster (Aster tartaricus) plant, in which the extraction is performed by use of water or 10-95% (v/v) ethanol as an extractant to obtain an extraction mixture. In some embodiments, the extraction mixture is further subject to column chromatography, in which the cloumn was eluted in sequence with water, and at least one eluent other than water.
Abstract translation: 本文公开了使用来自Aster物质的提取物来制备用于治疗疼痛的药物。 提取物是从新鲜和/或干燥的根状和根状茎中提取的，其中通过使用水或10-95％（v / v）乙醇作为萃取剂进行提取，从而得到一种 提取混合物。 在一些实施方案中，萃取混合物进一步进行柱色谱法，其中色谱柱依次用水和至少一种除水以外的洗脱液洗脱。
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公开(公告)号：US20150224159A1
公开(公告)日：2015-08-13
申请号：US14613065
申请日：2015-02-03
Inventor： Leah Lo , Win-Chin Chiang , Jui-Ching Chen , Yu-Min Lin , Chien-Chang Wu , Che-Yi Lin , Chien-Jen Shih , Yu-Hsuan Lin , Tzu-Chun Chen , Yu-Hsiang Huang
IPC: A61K36/535 , A61K31/352 , A61K31/216
CPC classification number: A61K36/535 , A61K31/216 , A61K31/352 , A61K2236/00 , A61K2300/00
Abstract: Disclosed is an extract of Perilla frutescens seeds that contains rosmarinic acid, luteolin, and apigenin, the weight ratio between rosmarinic acid, luteolin, and apigenin being 0.1-200:0.1-200:1. Also disclosed is a method for treating a psychiatric disorder using the above-described extract or an extract of Perilla frutescens seeds containing at least an active agent selected from the group consisting of rosmarinic acid, luteolin, and apigenin.
Abstract translation: 公开了含有迷迭香酸，木犀草素和芹菜素的紫苏属种子提取物，迷迭香酸，木犀草素和芹菜素的重量比为0.1-200：0.1〜200：1。 还公开了使用上述提取物或含有至少一种选自迷迭香酸，木犀草素和芹菜素的活性剂的紫苏属种子提取物治疗精神病的方法。
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