公开(公告)号：US12121557B2

公开(公告)日：2024-10-22

申请号：US17832801

申请日：2022-06-06

申请人： ARJUNA NATURAL PRIVATE LIMITED

发明人： Benny Antony

IPC分类号： A61K36/21 ,  A61K9/00 ,  A61K9/20 ,  A61K9/68 ,  A61K31/194 ,  A61K31/198 ,  A61K31/366 ,  A61K31/375 ,  A61K31/70 ,  A61K33/00 ,  A61K36/185 ,  A61K36/88 ,  A61K38/00

CPC分类号： A61K36/21 ,  A61K9/0053 ,  A61K9/0056 ,  A61K9/0058 ,  A61K9/0095 ,  A61K9/20 ,  A61K31/194 ,  A61K31/198 ,  A61K31/366 ,  A61K31/375 ,  A61K31/70 ,  A61K33/00 ,  A61K36/185 ,  A61K36/88 ,  A61K38/00 ,  A61K2236/00 ,  A61K2236/15 ,  A61K2236/33 ,  A61K2236/331 ,  A61K2236/35 ,  A61K2236/39 ,  A61K2236/51 ,  A61K2236/53

摘要： An extract of Amaranth, having enriched nitrate content, L-arginine, Flavonoids, saponins, alkaloids, carbohydrates, proteins, potassium, and with negligible amount of oxalic acid or oxalate content. The extract of Amaranth can be prepared from fresh or dried leaves and stem of Amaranth. Dosage forms of extract include fast melt tablet, lozenge, candy, chewing gum, beverage, tablet, capsule, pill, and powder. The extract of Amaranth enhances nitric oxide concentration, enhances nitrate level concentration, and enhances nitrite level in blood as well as in saliva. Administering the extract can lower blood pressure, increase physical endurance, increase swimming endurance, increase running endurance, and improve sexual performance among human beings.

公开(公告)号：US20240116970A1

公开(公告)日：2024-04-11

申请号：US18470691

申请日：2023-09-20

申请人： PURECIRCLE SDN BHD

发明人： Avetik MARKOSYAN

IPC分类号： C07H15/256 ,  A21D2/18 ,  A23C9/13 ,  A23G1/40 ,  A23G3/42 ,  A23G9/34 ,  A23L2/02 ,  A23L2/60 ,  A23L27/30 ,  A23L27/50 ,  A61K8/60 ,  A61K31/7034 ,  A61K31/704 ,  A61K36/28 ,  A61Q11/00 ,  B01D15/18 ,  B01D15/42 ,  C07H1/06 ,  C07H1/08

CPC分类号： C07H15/256 ,  A21D2/181 ,  A23C9/1307 ,  A23G1/40 ,  A23G3/42 ,  A23G9/34 ,  A23L2/02 ,  A23L2/60 ,  A23L27/36 ,  A23L27/50 ,  A61K8/602 ,  A61K31/7034 ,  A61K31/704 ,  A61K36/28 ,  A61Q11/00 ,  B01D15/1871 ,  B01D15/1885 ,  B01D15/426 ,  C07H1/06 ,  C07H1/08 ,  A23V2002/00 ,  A61K2236/00

摘要： Methods of preparing highly purified steviol glycosides, particularly Rebaudioside D, are described. The methods include purification from the extraction stage of the Stevia rebaudiana Bertoni plant, purification of steviol glycoside mixtures, Rebaudioside D and Rebaudioside A from a commercial Stevia extract, and purification of Rebaudioside D from remaining solutions obtained after isolation and purification of Rebaudioside A and a high purity mixture of steviol glycosides. The methods are useful for producing high purity Rebaudioside D, Rebaudioside A, and steviol glycoside mixtures. The high purity steviol glycosides are useful as non-caloric sweeteners in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

公开(公告)号：US11793883B2

公开(公告)日：2023-10-24

申请号：US17937463

申请日：2022-10-03

申请人： DAY THREE LABS MANUFACTURING INC.

发明人： William Z. Levine ,  Shmuel Cohen

IPC分类号： A61K47/64 ,  A61K31/352 ,  A61K36/185

CPC分类号： A61K47/643 ,  A61K31/352 ,  A61K36/185 ,  A61K2236/00

摘要： Embodiments of the invention relate to methods for the manufacture of a protein-bound cannabinoid, comprising: obtaining a cannabinoid or cannabis in a form selected from the group consisting of cannabis smoke, cannabis vapor, cannabinoid solution and cannabis extract, and combining the cannabis smoke, vapor, cannabinoid solution or cannabis extract with an aqueous solution or suspension comprising a plasma protein to form a protein-bound cannabinoid. Further embodiments relate to aqueous solutions comprising a plasma protein-bound cannabinoid and pharmaceutical compositions comprising cannabinoids bound to plasma protein.

公开(公告)号：US11712055B2

公开(公告)日：2023-08-01

申请号：US17481945

申请日：2021-09-22

申请人： PURECIRCLE SDN. BHD.

发明人： Avetik Markosyan

IPC分类号： A23L27/30 ,  A23L2/60 ,  C07H1/08 ,  C07H15/24 ,  A61K8/63 ,  A61Q11/00 ,  C07H15/256 ,  A61K36/28 ,  A61K8/9789 ,  A61K8/9794

CPC分类号： A23L27/33 ,  A23L2/60 ,  A23L27/36 ,  A61K8/63 ,  A61K8/9789 ,  A61K8/9794 ,  A61K36/28 ,  A61Q11/00 ,  C07H1/08 ,  C07H15/24 ,  C07H15/256 ,  A61K2236/00

摘要： Stevia compositions are prepared from steviol glycosides of Stevia rebaudiana Bertoni. The compositions are able to provide a superior taste profile and can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals.

公开(公告)号：US20190216112A1

公开(公告)日：2019-07-18

申请号：US16334412

申请日：2017-09-19

申请人： West Invest S.A.

发明人： Eric REYNAUD ,  Charles DUVAL ,  Stanislas BAUDOUIN ,  Jacques MEURISSE

IPC分类号： A23L2/78 ,  A23L2/02 ,  A23L33/105

CPC分类号： A23L2/78 ,  A23L2/02 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/30 ,  A23V2250/21166 ,  A23V2300/34 ,  A61K36/45 ,  A61K2236/00

摘要： The invention relates to a deacidified juice, as well as a process for deacidifying a cranberry juice to be deacidified that is eluted on a bed or a weak anion exchange resin at a rate (BV/h) such that the deacidified cranberry juice leaving the elution has a pH=pKa1 (malic acid)

公开(公告)号：US20190201467A1

公开(公告)日：2019-07-04

申请号：US16299683

申请日：2019-03-12

申请人： KING SAUD UNIVERSITY

发明人： Awaad Amani SHAFEEK ,  Reham Moustafa EL-MELIGY ,  Mohammed Sobhy MARZOUK ,  Shroog Mohamed ALOTAIBY

IPC分类号： A61K36/31 ,  C07C51/42 ,  A61K31/22 ,  A61K31/20 ,  C11B1/10 ,  B01D15/42 ,  C07C67/58 ,  A61K9/00 ,  C07C67/56 ,  B01D11/02 ,  A61K31/225 ,  C07C51/47

CPC分类号： A61K36/31 ,  A61K9/0053 ,  A61K31/20 ,  A61K31/22 ,  A61K31/225 ,  A61K2236/00 ,  A61K2236/33 ,  B01D11/0288 ,  B01D11/0292 ,  B01D15/426 ,  C07C51/42 ,  C07C51/47 ,  C07C67/56 ,  C07C67/58 ,  C11B1/10 ,  A61K2300/00 ,  C07C69/675 ,  C07C53/126 ,  C07C59/90

摘要： The present invention relates to extracts, compounds isolated from Cakile arabica for use in the treatment of ulcer and to pharmaceutical compositions thereof.

公开(公告)号：US20190151395A1

公开(公告)日：2019-05-23

申请号：US16160847

申请日：2018-10-15

申请人： Donatella Paolino ,  Gioacchino Folino Gallo ,  Massimo Fresta ,  Leone Spataro

发明人： Donatella Paolino ,  Gioacchino Folino Gallo ,  Massimo Fresta ,  Leone Spataro ,  Alessandro Venditti

IPC分类号： A61K36/83 ,  A61Q5/00 ,  A61K9/107 ,  A61K8/02 ,  A61K8/97 ,  A61Q19/00 ,  A61K9/06 ,  A61K9/00

CPC分类号： A61K36/83 ,  A61K8/0216 ,  A61K8/97 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/107 ,  A61K2236/00 ,  A61K2236/33 ,  A61Q5/006 ,  A61Q19/008

摘要： The invention relates to an extract obtained from Daphne laureola L to be used the pharmaceutical cosmetic and cosmeceutical field for the topical treatment of dermopathies in general and of psoriasis in particular, by means of the topical application of effective amounts of said extracts. The invention also relates to the pharmaceutical, cosmetic and cosmeceutical compositions comprising the Daphne laureola extracts. The invention also relates to the topical treatment of dermopathies in general and of psoriasis in particular.

公开(公告)号：US20180354879A1

公开(公告)日：2018-12-13

申请号：US15764941

申请日：2016-10-13

申请人： NATUREX, S. A. ,  UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE

发明人： Natacha ROMBAUT ,  Anne-Sylvie FABIANO TIXIER ,  Simona BIRTIC ,  Antoine Charles BILY ,  Marc ROLLER ,  Farid CHEMAT

IPC分类号： C07C35/08 ,  A23L33/105 ,  B01D11/02

CPC分类号： C07C35/08 ,  A23L33/105 ,  A23V2002/00 ,  A61K2236/00 ,  B01D11/0288

摘要： The invention relates to a novel organic solubilisation and/or extraction solvent comprising at least one compound selected from the group of saturated monocyclic terpenoids, to an extraction method using said solvent, and to extracts obtained by said method.More particularly, the invention relates to a novel use of para-menthane, a saturated terpenoid compound, as a solvent derived from natural substances, and also to a solvent comprising para-menthane.

公开(公告)号：US20180344787A1

公开(公告)日：2018-12-06

申请号：US15777891

申请日：2016-11-02

申请人： NATURAL RESPONSE, S.A.

发明人： Leandro Padilla Iglesias ,  Andres Valencia Michaud

IPC分类号： A61K36/185

CPC分类号： A61K36/185 ,  A61K36/25 ,  A61K36/48 ,  A61K36/73 ,  A61K36/77 ,  A61K36/896 ,  A61K2236/00 ,  A61K2236/15 ,  A61K2236/17 ,  A61K2236/331 ,  A61K2236/53

摘要： The present application relates to a method for obtaining and purifying saponins from plant extracts, through a series of salting and filtrations steps, to provide high purity saponin extracts on large scale.

公开(公告)号：US20180318371A1

公开(公告)日：2018-11-08

申请号：US15772810

申请日：2016-11-03

申请人： Academia Sinica ,  Industrial Technology Research Institute

发明人： Chang-Jen HUANG ,  Rita P.-Y. CHEN ,  Yung-Feng LIAO ,  Bo-Kai WU ,  Po-Ting CHEN ,  Hui-Ping TSAI ,  Yi-Cheng CHENG ,  Cheng-Li FANG ,  Hung-Chi CHIEN ,  Tien-Soung TONG ,  Ting-Shou CHEN ,  Shu-Jiau CHIOU

IPC分类号： A61K36/48 ,  A61P25/28 ,  A61K9/00

CPC分类号： A61K36/48 ,  A61K2236/00

摘要： Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.