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1.发明授权公开(公告)号：US11045652B2
公开(公告)日：2021-06-29
申请号：US16395320
申请日：2019-04-26
Applicant: Medtronic, Inc.
Inventor： Jadin C. Jackson , Yizi Xiao , Paula Andrea Elma Dassbach Green , Jianping Wu , Christopher L. Pulliam , Eric J. Panken , Robert S. Raike , Scott R. Stanslaski
Abstract: Techniques are described determining electrodes that are proximate or distal to location of an oscillatory signal source in a patient based on current source densities (CSDs). Processing circuitry may determine, for one or more electrodes of a plurality of electrodes, respective time-varying measurements of CSDs, aggregate, for the one or more electrodes of the plurality electrodes, the respective time-varying measurements of the CSDs to generate respective average level values for the one or more electrodes of the plurality of electrodes, determine, for one or more electrodes of the plurality of electrodes, respective phase-magnitude representations of the time-varying measurements of the CSDs. The respective phase-magnitude representations are indicative of respective magnitudes and phases of a particular frequency component of respective time-varying measurements of the CSDs. The particular frequency component is a frequency component having a largest transform coefficient in a time-varying measurement of a CSD having a largest average level value.
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公开(公告)号：US11033742B2
公开(公告)日：2021-06-15
申请号：US16392129
申请日：2019-04-23
Applicant: Medtronic, Inc.
Inventor： Eric J. Panken , Jadin C. Jackson , Yizi Xiao , Christopher L. Pulliam
Abstract: Techniques are disclosed for using probabilistic entropy to select electrodes with fewer artifacts for controlling adaptive electrical neurostimulation. In one example, a plurality of electrodes sense bioelectrical signals of a brain of a patient. Processing circuitry determines, for each bioelectrical signal sensed at a respective electrode of the plurality of electrodes, a probabilistic entropy value of the bioelectrical signal. The processing circuitry compares each of the respective probabilistic entropy values of the bioelectrical signal to respective entropy threshold values and selects, based on the comparisons, a subset of electrodes of the plurality of electrodes. The processing circuitry controls, based on the bioelectrical signals sensed via respective electrodes of the subset of electrodes and excluding the bioelectrical signals of the plurality of bioelectrical signals sensed via respective electrodes not in the subset of electrodes, delivery of electrical stimulation therapy to the patient.
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Patent Agency Ranking
公开(公告)号：US11318296B2
公开(公告)日：2022-05-03
申请号：US16172435
申请日：2018-10-26
Applicant: Medtronic, Inc.
Inventor： Yizi Xiao , Eric J. Panken , Scott R. Stanslaski , Jadin C. Jackson , Christopher Pulliam
Abstract: Techniques are disclosed to automate determination of therapy parameter values for adaptive deep brain stimulation (aDBS). A medical device may determine differences in power values between a present and a previous power value. Based on the difference being greater than or equal to a threshold value, the medical device may iteratively adjust a present therapy parameter value until the difference in the power values between a present and a previous power value is less than the threshold value.
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4.发明申请公开(公告)号：US20200338353A1
公开(公告)日：2020-10-29
申请号：US16395320
申请日：2019-04-26
Applicant: Medtronic, Inc.
Inventor： Jadin C. Jackson , Yizi Xiao , Paula Andrea Elma Dassbach Green , Jianping Wu , Christopher L. Pulliam , Eric J. Panken , Robert S. Raike , Scott R. Stanslaski
Abstract: Techniques are described determining electrodes that are proximate or distal to location of an oscillatory signal source in a patient based on current source densities (CSDs). Processing circuitry may determine, for one or more electrodes of a plurality of electrodes, respective time-varying measurements of CSDs, aggregate, for the one or more electrodes of the plurality electrodes, the respective time-varying measurements of the CSDs to generate respective average level values for the one or more electrodes of the plurality of electrodes, determine, for one or more electrodes of the plurality of electrodes, respective phase-magnitude representations of the time-varying measurements of the CSDs. The respective phase-magnitude representations are indicative of respective magnitudes and phases of a particular frequency component of respective time-varying measurements of the CSDs. The particular frequency component is a frequency component having a largest transform coefficient in a time-varying measurement of a CSD having a largest average level value.
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公开(公告)号：US11135429B2
公开(公告)日：2021-10-05
申请号：US16395308
申请日：2019-04-26
Applicant: Medtronic, Inc.
Inventor： Eric J. Panken , Christopher L. Pulliam , Jadin C. Jackson , Yizi Xiao
IPC: A61B5/00 , A61B5/24 , A61B5/369 , A61N1/05 , A61N1/36 , A61N1/372 , G01B7/00 , G16H20/30 , G16H50/20 , G16H50/50
Abstract: Techniques are described to determine a location of at least one oscillatory signal source in a patient. Processing circuitry may determine expected electrical signal levels based on a hypothetical location of the at least one oscillatory signal source. Processing circuitry may determine the electrical signal levels and determine an error value based on the expected electrical signal levels and the determined electrical signal levels. Processing circuitry may adjust the hypothetical location of the at least one oscillatory signal source until the error value is less than or equal to a threshold value, including the example where the error value is minimized.
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公开(公告)号：US20200338351A1
公开(公告)日：2020-10-29
申请号：US16395308
申请日：2019-04-26
Applicant: Medtronic, Inc.
Inventor： Eric J. Panken , Christopher L. Pulliam , Jadin C. Jackson , Yizi Xiao
Abstract: Techniques are described to determine a location of at least one oscillatory signal source in a patient. Processing circuitry may determine expected electrical signal levels based on a hypothetical location of the at least one oscillatory signal source. Processing circuitry may determine the electrical signal levels and determine an error value based on the expected electrical signal levels and the determined electrical signal levels. Processing circuitry may adjust the hypothetical location of the at least one oscillatory signal source until the error value is less than or equal to a threshold value, including the example where the error value is minimized.
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公开(公告)号：US20200338350A1
公开(公告)日：2020-10-29
申请号：US16392129
申请日：2019-04-23
Applicant: Medtronic, Inc.
Inventor： Eric J. Panken , Jadin C. Jackson , Yizi Xiao , Christopher L. Pulliam
IPC: A61N1/36 , A61B5/00 , A61B5/0478 , A61N1/372 , A61N1/05
Abstract: Techniques are disclosed for using probabilistic entropy to select electrodes with fewer artifacts for controlling adaptive electrical neurostimulation. In one example, a plurality of electrodes sense bioelectrical signals of a brain of a patient. Processing circuitry determines, for each bioelectrical signal sensed at a respective electrode of the plurality of electrodes, a probabilistic entropy value of the bioelectrical signal. The processing circuitry compares each of the respective probabilistic entropy values of the bioelectrical signal to respective entropy threshold values and selects, based on the comparisons, a subset of electrodes of the plurality of electrodes. The processing circuitry controls, based on the bioelectrical signals sensed via respective electrodes of the subset of electrodes and excluding the bioelectrical signals of the plurality of bioelectrical signals sensed via respective electrodes not in the subset of electrodes, delivery of electrical stimulation therapy to the patient.
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