专利检索 ap:("Merck Sharp & Dohme Corp.") AND inv:"Ashwin Rao" 第 1 页

1.

发明申请
COMPOUNDS USEFUL FOR ALTERING THE LEVELS OF BILE ACIDS FOR THE TREATMENT OF DIABETES AND CARDIOMETABOLC DISEASE 审中-公开

公开(公告)号：US20190218224A1

公开(公告)日：2019-07-18

申请号：US16324604

申请日：2017-08-10

申请人： Merck Sharp & Dohme Corp.

发明人： John P. Caldwell , Mary Ann Caplen , Jared N. Cumming , Kevin D. Dykstra , Alan Hruza , Claire Lankin , Derun Li , Hong Liu , Amy McCracken , Brian McKittrick , Ashwin Rao , Jayaram Tagat , Haiqun Tang , Brandon M. Taoka , Andreas Verras , Shawn P. Walsh , Wen-Lian Wu , Tianyuan Zhang

IPC分类号： C07D487/04 , C07D519/00 , C07D498/04

CPC分类号： C07D487/04 , C07D498/04 , C07D519/00

摘要： Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.

2.

发明授权
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease 有权

公开(公告)号：US10414775B2

公开(公告)日：2019-09-17

申请号：US16324604

申请日：2017-08-10

申请人： Merck Sharp & Dohme Corp.

发明人： John P. Caldwell , Mary Ann Caplen , Jared N. Cumming , Kevin D. Dykstra , Alan Hruza , Claire Lankin , Derun Li , Hong Liu , Amy McCracken , Brian McKittrick , Ashwin Rao , Jayaram Tagat , Haiqun Tang , Brandon M. Taoka , Andreas Verras , Shawn P. Walsh , Wen-Lian Wu , Tianyuan Zhang

IPC分类号： C07D519/00 , C07D487/04 , C07D498/04

摘要： Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.