-
公开(公告)号：US20170008906A1
公开(公告)日：2017-01-12
申请号：US15272669
申请日：2016-09-22
发明人： Craig A. Coburn , Steven W. Ludmerer , Kun Liu , Hao Wu , Richard Soll , Bin Zhong , Jian Zhu
IPC分类号： C07D498/04 , A61K31/4178 , A61K31/553 , A61K45/06 , A61K31/5365
CPC分类号： C07D498/04 , A61K31/4025 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/423 , A61K31/437 , A61K31/4439 , A61K31/4985 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K38/05 , A61K38/06 , A61K45/06 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D498/10 , C07K5/06 , C07K5/08
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译： 本发明涉及可用作丙型肝炎病毒（HCV）NS5A抑制剂，这种化合物的合成以及这些化合物用于抑制HCV NS5A活性用于治疗或预防HCV感染的用途的式（I）化合物和 抑制基于细胞的系统中的HCV病毒复制和/或病毒生产。
-
公开(公告)号：US20140371138A1
公开(公告)日：2014-12-18
申请号：US14473117
申请日：2014-08-29
发明人： Craig A. Coburn , John A. McCauley , Steven W. Ludmerer , Kun Liu , Joseph P. Vacca , Hao Wu , Bin Hu , Richard Soll , Fei Sun , Xinghai Wang , Man Yan , Chengren Zhang , Mingwei Zheng , Bin Zhong , Jian Zhu
IPC分类号： C07K5/08 , A61K38/05 , A61K38/06 , C07D471/04 , A61K31/437 , C07K5/06 , A61K45/06
CPC分类号： C07D498/04 , A61K31/4025 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/423 , A61K31/437 , A61K31/4439 , A61K31/4985 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K38/05 , A61K38/06 , A61K45/06 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D498/10 , C07K5/06 , C07K5/08
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译： 本发明涉及可用作丙型肝炎病毒（HCV）NS5A抑制剂，这种化合物的合成以及这些化合物用于抑制HCV NS5A活性用于治疗或预防HCV感染的用途的式（I）化合物和 抑制基于细胞的系统中的HCV病毒复制和/或病毒生产。
-
公开(公告)号：US11053243B2
公开(公告)日：2021-07-06
申请号：US16829878
申请日：2020-03-25
发明人： Craig A. Coburn , Steven W. Ludmerer , Kun Liu , Hao Wu , Richard Soil , Bin Zhong , Jian Zhu
IPC分类号： C07D471/04 , C07D407/14 , C07D487/04 , C07D401/14 , C07D403/14 , C07D403/12 , C07D413/14 , C07D405/14 , C07D405/12 , C07D417/14 , C07D409/14 , A61K31/4985 , A61K31/4439 , A61K31/4184 , A61K31/423 , A61K31/4025 , A61K31/519 , A61K31/404 , A61K31/506 , A61K31/5377 , A61K31/427 , A61K31/4245 , A61K31/475 , A61K31/536 , A61K31/4178 , A61K31/517 , A61K31/5386 , A61K31/553 , A61K31/437
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
-
公开(公告)号：US20220356182A1
公开(公告)日：2022-11-10
申请号：US17324799
申请日：2021-05-19
发明人： Craig A. Coburn , Steven W. Ludmerer , Kun Liu , Hao Wu , Richard Soll , Bin Zhong , Jian Zhu
IPC分类号： C07D471/04 , C07D407/14 , A61K31/4985 , A61K31/4439 , A61K31/4184 , A61K31/423 , A61K31/4025 , A61K31/519 , A61K31/404 , A61K31/506 , A61K31/5377 , A61K31/427 , A61K31/4245 , A61K31/475 , A61K31/536 , A61K31/4178 , A61K31/517 , A61K31/5386 , A61K31/553 , C07D487/04 , C07D401/14 , C07D403/14 , C07D403/12 , C07D413/14 , C07D405/14 , C07D405/12 , C07D417/14 , C07D409/14 , A61K31/437
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
-
公开(公告)号：US20200262836A1
公开(公告)日：2020-08-20
申请号：US16829878
申请日：2020-03-25
发明人： CRAIG A. COBURN , STEVEN W. LUDMERER , KUN LIU , Hao Wu , Richard Soll , Bin Zhong , Jian Zhu
IPC分类号： C07D471/04 , A61K31/437 , C07D409/14 , C07D417/14 , C07D405/12 , C07D405/14 , C07D413/14 , C07D403/12 , C07D403/14 , C07D401/14 , C07D487/04 , A61K31/553 , A61K31/5386 , A61K31/517 , A61K31/4178 , A61K31/536 , A61K31/475 , A61K31/4245 , A61K31/427 , A61K31/5377 , A61K31/506 , A61K31/404 , A61K31/519 , A61K31/4025 , A61K31/423 , A61K31/4184 , A61K31/4439 , A61K31/4985 , C07D407/14
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
-
公开(公告)号：US09090661B2
公开(公告)日：2015-07-28
申请号：US14473117
申请日：2014-08-29
发明人： Craig A. Coburn , John A. McCauley , Steven W. Ludmerer , Kun Liu , Joseph P. Vacca , Hao Wu , Bin Hu , Richard Soll , Fei Sun , Xinghai Wang , Man Yan , Chengren Zhang , Mingwei Zheng , Bin Zhong , Jian Zhu
IPC分类号： A61K31/4178 , C07D405/14 , C07K5/08 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D409/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D498/10 , A61K31/437 , A61K38/05 , A61K38/06 , A61K45/06 , C07K5/06
CPC分类号： C07D498/04 , A61K31/4025 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/423 , A61K31/437 , A61K31/4439 , A61K31/4985 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K38/05 , A61K38/06 , A61K45/06 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D498/10 , C07K5/06 , C07K5/08
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译： 本发明涉及可用作丙型肝炎病毒（HCV）NS5A抑制剂，这种化合物的合成以及这些化合物用于抑制HCV NS5A活性用于治疗或预防HCV感染的用途的式（I）化合物和 抑制基于细胞的系统中的HCV病毒复制和/或病毒生产。
-
公开(公告)号：US20190127365A1
公开(公告)日：2019-05-02
申请号：US15800172
申请日：2017-11-01
发明人： Craig A. Coburn , Steven W. Ludmerer , Kun Liu , Hao Wu , Richard Soll , Bin Zhong , Jian Zhu
IPC分类号： C07D471/04 , A61K31/437 , A61K31/4985 , A61K31/4439 , A61K31/4184 , A61K31/423 , A61K31/4025 , A61K31/519 , A61K31/404 , A61K31/506 , A61K31/5377 , A61K31/427 , A61K31/4245 , A61K31/475 , A61K31/536 , A61K31/4178 , A61K31/517 , A61K31/5386 , A61K31/553 , C07D487/04 , C07D401/14 , C07D403/14 , C07D403/12 , C07D413/14 , C07D405/14 , C07D405/12 , C07D417/14 , C07D409/14 , C07D407/14
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
-
公开(公告)号：US20150246917A1
公开(公告)日：2015-09-03
申请号：US14711345
申请日：2015-05-13
发明人： Craig A. Coburn , Steven W. Ludmerer , Kun Liu , Hao Wu , Richard Soll , Bin Zhong , Jian Zhu
IPC分类号： C07D471/04 , C07D487/04 , A61K31/4985 , C07D401/14 , A61K31/4439 , C07D403/14 , A61K31/4184 , C07D403/12 , C07D413/14 , A61K31/423 , C07D405/14 , A61K31/4025 , C07D405/12 , A61K31/404 , A61K31/506 , A61K31/5377 , C07D498/04 , A61K31/5383 , A61K31/553 , A61K45/06 , A61K31/437
CPC分类号： C07D498/04 , A61K31/4025 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/423 , A61K31/437 , A61K31/4439 , A61K31/4985 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K38/05 , A61K38/06 , A61K45/06 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D498/10 , C07K5/06 , C07K5/08
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译： 本发明涉及可用作丙型肝炎病毒（HCV）NS5A抑制剂，这种化合物的合成以及这些化合物用于抑制HCV NS5A活性用于治疗或预防HCV感染的用途的式（I）化合物和 抑制基于细胞的系统中的HCV病毒复制和/或病毒生产。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.023 秒)
