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公开(公告)号：US11124478B2
公开(公告)日：2021-09-21
申请号：US16795745
申请日：2020-02-20
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D207/09 , C07D207/08 , C12P17/10
摘要： The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions:
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公开(公告)号：US09809536B2
公开(公告)日：2017-11-07
申请号：US14354161
申请日：2012-10-22
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D207/09 , C07D207/08 , C12P17/10
CPC分类号： C07D207/09 , C07D207/08 , C12P17/10
摘要： The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions.
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公开(公告)号：US11767292B2
公开(公告)日：2023-09-26
申请号：US17478601
申请日：2021-09-17
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D207/09 , C07D207/08 , C12P17/10
CPC分类号： C07D207/09 , C07D207/08 , C12P17/10
摘要： The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions:
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公开(公告)号：US11708371B2
公开(公告)日：2023-07-25
申请号：US17155982
申请日：2021-01-22
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D487/04 , C07D403/12 , C07D207/09 , C07D263/06 , A61K31/4196 , A61K31/519
CPC分类号： C07D487/04 , A61K31/4196 , A61K31/519 , C07D207/09 , C07D263/06 , C07D403/12 , C07B2200/13
摘要： The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
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公开(公告)号：US10899771B2
公开(公告)日：2021-01-26
申请号：US16590180
申请日：2019-10-01
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D487/04 , C07D403/12 , C07D207/09 , C07D263/06 , A61K31/4196 , A61K31/519
摘要： The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
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公开(公告)号：US10435410B2
公开(公告)日：2019-10-08
申请号：US16133320
申请日：2018-09-17
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D487/04 , C07D403/12 , C07D207/09 , C07D263/06 , A61K31/4196 , A61K31/519
摘要： The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
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公开(公告)号：US09822121B2
公开(公告)日：2017-11-21
申请号：US15057427
申请日：2016-03-01
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D487/04 , C07D263/06 , C07D207/09 , C07D403/12 , A61K31/4196 , A61K31/519
CPC分类号： C07D487/04 , A61K31/4196 , A61K31/519 , C07B2200/13 , C07D207/09 , C07D263/06 , C07D403/12
摘要： The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
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公开(公告)号：US20190016729A1
公开(公告)日：2019-01-17
申请号：US16133320
申请日：2018-09-17
发明人： John Y.L. Chung , Kevin Campos , Edwards Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D487/04 , C07D263/06 , C07D207/09 , C07D403/12 , A61K31/4196 , A61K31/519
CPC分类号： C07D487/04 , A61K31/4196 , A61K31/519 , C07B2200/13 , C07D207/09 , C07D263/06 , C07D403/12
摘要： The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
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公开(公告)号：US20160176884A1
公开(公告)日：2016-06-23
申请号：US15057427
申请日：2016-03-01
发明人： John Y.L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R. Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D487/04 , C07D403/12 , C07D207/09
CPC分类号： C07D487/04 , A61K31/4196 , A61K31/519 , C07B2200/13 , C07D207/09 , C07D263/06 , C07D403/12
摘要： The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
摘要翻译： 本发明涉及制备式（I）和式（II）及其中间体的β3激动剂的方法。 β3激动剂可用于治疗某些疾病，包括膀胱过度活动症，尿失禁和尿急。
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公开(公告)号：US10577316B2
公开(公告)日：2020-03-03
申请号：US15715493
申请日：2017-09-26
发明人： John Y. L. Chung , Kevin Campos , Edward Cleator , Robert F. Dunn , Andrew Gibson , R Scott Hoerrner , Stephen Keen , Dave Lieberman , Zhuqing Liu , Joseph Lynch , Kevin M. Maloney , Feng Xu , Nobuyoshi Yasuda , Naoki Yoshikawa , Yong-Li Zhong
IPC分类号： C07D207/09 , C07D207/08 , C12P17/10
摘要： The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions:
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